Search for dissertations about: "intrahost evolution"

Found 2 swedish dissertations containing the words intrahost evolution.

  1. 1. Intrahost evolution of HIV-1 phenotypes

    Author : Marie Borggren; Avdelningen för medicinsk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : HIV-1 evolves constantly within an infected individual, due to its mutation-prone viral enzyme, high viral turnover and pressure from the host immune system. Therefore, viruses isolated at different time points from the same individual are never exactly the same and, accordingly, rarely function the same way. READ MORE

  2. 2. Genetic dynamics of HIV-1 : Recombination, drug resistance and intrahost evolution

    Author : Karin Wilbe; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; HIV-1; genetic evolution; recombination; drug resistance; intrahost evolution;

    Abstract : A striking characteristic of HIV is the enormous capacity of genetic variation. Frequent mutations, deletions, insertions and recombination events create a population of genetically related but non-identical viruses that is under constant change and ready to adapt to environmental changes. READ MORE