Search for dissertations about: "intraluminal pressure"

Showing result 1 - 5 of 22 swedish dissertations containing the words intraluminal pressure.

2. 1. Regulation of vascular function by fluid mechanical forces. Development of a new vascular experimental platform for integrative physiological and molecular biological studies of living conduit vessels

   Author : Li-Ming Gan; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; perfusion model; endothelium; smooth muscle cells; shear stress; pressure; nitric oxide; endothelin-1; vascular endothelial growth factor; c-jun; c-fos; real-time PCR; NO probe.;

   Abstract : The vascular endothelium is a multifunctional interface between blood flow and target organs and is continuously exposed to fluid mechanical forces such as shear stress, compressive, and tensile forces. Both in vivo and in vitro data indicate that biomechanical forces exert important modulating effects on key vascular functions. READ MORE

4. 2. Methodological studies of eicosanoid enzyme gene expression in vascular endothelium exposed to biomechanical stress

   Author : Roya Doroudi; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostanoids; endothelium; quantitative RT-PCR; perfusion model; shear stress; intraluminal pressure; immediate-early genes;

   Abstract : Prostaglandins are the major eicosanoids synthesized by vascular endothelial cells, and the vasculature is an important target organ for their bioactive metabolites. In vitro studies have shown that biomechanical forces are important regulators of vascular expression of prostanoid enzymes and release of metabolites. READ MORE

5. 3. Experimental studies of the regulations of synthesis and release of tissue-type plasminogen activator from vascular endothelium

   Author : Lena Selin Sjögren; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tissue-type plasminogen activator; endothelium; fluid mechanical forces; shear stress; pressure; immunohistochemistry; gene expression;

   Abstract : The fibrinolytic system has several important functions and one crucial function is the prevention and removal of fibrin deposits in blood vessels. Tissue-type plasminogen activator (t-PA) plays a key role in this process, and in vitro data suggest that an acute release of t-PA is induced as a thromboprotective response whenever clotting mechanisms are initiated. READ MORE

6. 4. Effects of Biomechanical Stress on Gene Regulation in Vascular Cells

   Author : Maria Carlström; Göteborgs universitet; []
   Keywords : shear stress; intraluminal pressure; endothelium; gene expression; DNA microarray; real-time RT-PCR; reference genes; smooth muscle cells; P2 receptors; TNF-alpha; urokinase-type plasminogen activator;

   Abstract : The vascular vessel wall is constantly exposed to biomechanical forces, such as shear and tensile stress. Biomechanical forces are important for several physiological and pathological processes and have been shown to regulate a number of fundamental vascular functions, such as vascular tone and remodeling processes. READ MORE

7. 5. Intra-abdominal Hypertension and Colonic Hypoperfusion after Abdominal Aortic Aneurysm Repair

   Author : Khatereh Djavani Gidlund; Martin Björck; Anders Wanhainen; Johan Valtysson; Martin Malina; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Abdominal aneurysm; Intra-abdomnial hypertension; Abdominal compartment syndrome; Colonic ischaemia; Colonic hypotension; Intra-abdominal pressure; rupture abdominal aortic aneurysm; Vascular surgery; Kärlkirurgi; Kirurgi; Surgery;

   Abstract : Colonic ischaemia (CI), Intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) are devastating complications after abdominal aortic aneurysm (AAA) surgery. The aims of this thesis were to study the incidence and clinical consequences of IAH/ACS and the association between CI and intra-abdominal pressure (IAP) among patients undergoing OR for ruptured AAA (rAAA), to compare extraluminal pHi monitoring, with standard intra-luminal monitoring among patients operated on for AAA, and to study the frequency and clinical consequences of IAH/ACS after endovascular repair (EVAR) for rAAA. READ MORE