Search for dissertations about: "intrathecal morphine"

Showing result 6 - 10 of 15 swedish dissertations containing the words intrathecal morphine.

2. 6. On cholecystokinin-opioid interaction in the spinal dorsal horn following peripheral nerve injury and inflammation

   Author : Guilherme de Araújo Lucas; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Cholecystokinin; Cholecystokinin receptors; Morphine; Spinal cord; Axotomy; Inflammation; Peptide release; Morphine tolerance; [my]-opioid receptor; Flexor reflex; Microdialysis;

   Abstract : The peptide cholecystokinin (CCK) antagonizes opioid-induced analgesia. Conversely, antagonists of CCK receptors enhance the analgesic effect of opioids. Together, these results support a role for CCK as an anti-opioid peptide in pain mechanisms. READ MORE

4. 7. Treatment of pain behavior after spinal cord injury in rats with special emphasis on the role of adenosine receptors

   Author : Margareta von Heijne; Karolinska Institutet; Karolinska Institutet; []
   Keywords : adenosine; adenosine receptors; allodynia; baclofen; central pain; clonidine; intrathecal; morphine; neuropathic pain; opioid; rat; R-phenylisopropyladenosine; spinal cord injury; tolerance;

   Abstract : Central pain is a form of neuropathic pain occurring after injury or dysfunction in the central nervous system, including the spinal cord. Allodynia (pain to innocuous stimuli) to mechanical and cold stimulation is a common feature of central pain and it is often resistant to treatment. READ MORE

5. 8. Fast track abdominal hysterectomy : On the mode of anesthesia, postoperative recovery and health economics

   Author : Ninnie Borendal Wodlin; Preben Kjølhede; Lena Nilsson; Christer Borgfeldt; Linköpings universitet; []
   Keywords : Abdominal hysterectomy; Cost-effectiveness; Fast track; General anesthesia; Health economy; Intrathecal morphine; Postoperative recovery Postoperative symptoms Randomized study; Spinal anesthesia; Quality of Life; MEDICINE; MEDICIN;

   Abstract : Introduction: Hysterectomy is the most common major gynecological operation in the Western World and approximately 5000 benign hysterectomies are performed in Sweden every year. Consequently it is a surgical procedure that affects many women. READ MORE

6. 9. The role of adenosine and its receptor subtypes in nociception and neuropathic pain

   Author : Weiping Wu; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Adenosine; adenosine receptors; antinociception; caffeine; knock-out mouse; neuropathy; morphine; R-PIA;

   Abstract : As neurotransmitter/modulator, adenosine plays an important role in nociceptive processing. Adenosine receptors are G-protein coupled and four receptor subtypes, A1, A2A, A2B and A3 have been identified. It is well established that adenosine and its receptor agonists produce primarily antinociceptive effect in animals and humans. READ MORE

7. 10. Opioids and regulation of breathing

   Author : Åsa Österlund Modalen; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Sameridine; partial - opioid agonist; local anesthetic; morphine; ventilation; respiratory depression; hypercarbia; hypoxia; frakefamide; peripheral -opioid agonist;

   Abstract : A most important challenge even in modern medicine is effective treatment of pain. Respiratory depression is the most feared side effect of analgesic treatment in the clinical situation. READ MORE