Search for dissertations about: "intron position conservation"
Found 3 swedish dissertations containing the words intron position conservation.
-
1. The relationship between orthology, protein domain architecture and protein function
Abstract : Lacking experimental data, protein function is often predicted from evolutionary and protein structure theory. Under the 'domain grammar' hypothesis the function of a protein follows from the domains it encodes. READ MORE
-
2. Molecular studies of multiple endocrine neoplasia type 1 (MEN1)
Abstract : Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant familial cancer syndrome characterized by tumors of the parathyroids, the endocrine pancreas and anterior pituitary. The MEN1 locus has been previously localized to chromosome 11q13 and subsequently a MEN1 minimum region was defined by a combination of linkage and tumor deletion studies. READ MORE
-
3. Analyses of protein evolution, function, and architecture
Abstract : Proteins can evolve over time in many different ways. An ancestral protein sequence inherited in different species will gradually undergo changes in primary sequence and sometimes in domain architecture. Some of these changes will affect its function, and evolutionary analyses can be used to predict function shift. READ MORE