Search for dissertations about: "invasive breast cancer"
Showing result 1 - 5 of 95 swedish dissertations containing the words invasive breast cancer.
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1. Breast cancer : Multifocality, heterogeneity, and related genetic signatures
Abstract : Breast carcinoma often exhibits a complex subgross morphology and may occupy a large volume of the breast tissue and show unifocal, multifocal or diffuse growth patterns. Expression of estrogen- and progesterone receptors, HER2 overexpression, tumor grade, and proliferative activity allows us to classify breast carcinoma into molecular subgroups (Luminal A, Luminal B, HER2-type, triple negative, and basal-like). READ MORE
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2. Molecular Cytogenetics in Sporadic Breast Cancer
Abstract : In recent time breast cancer has become the most common form of female cancer in the western world. It has been estimated that the lifetime risk of women falling ill from the disease is 10%. The number of patients diagnosed each year has been increasing steadily since the 1970s. READ MORE
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3. Aspects of Progression in Breast Carcinoma : from ductal carcinoma in situ to invasive cancer
Abstract : In the past decades our knowledge concerning breast cancer progression from ductal carcinoma in situ (DCIS) to invasive cancer has grown rapidly. However, molecular factors driving the progression are still largely unknown. READ MORE
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4. Wnt-5a Signalling in Human Mammary Cells: Implications for the Development of Breast Cancer
Abstract : The Wnt-5a gene encodes a secreted protein that regulates several normal processes in embryonic and adult tissues by as yet unknown mechanisms. Expression of Wnt-5a protein does not cause cell transformation, but it instead counteracts the effects induced by transforming Wnts. READ MORE
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5. Impact of Lifestyle, Hormones, and Genes on Breast Cancer
Abstract : Approximately 7000 women are diagnosed and 1500 women die from breast cancer in Sweden every year. The aim of this thesis was to study the interplay of polymorphisms, hormone levels, lifestyle, and the use of concomitant medication in relation to risk and prognosis in two cohorts: one composed of young healthy women from high-risk breast cancer families and the other of breast cancer patients from the general population. READ MORE