Search for dissertations about: "invasive carcinoma"

Showing result 1 - 5 of 103 swedish dissertations containing the words invasive carcinoma.

2. 1. Aspects of Progression in Breast Carcinoma : from ductal carcinoma in situ to invasive cancer

   Author : Wenjing Zhou; Fredrik Wärnberg; Marie-Louise Fjällskog; Carl Blomqvist; Malin Sund; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; progression; ductal carcinoma in situ; breast cancer; Medicinsk vetenskap; Medical Science;

   Abstract : In the past decades our knowledge concerning breast cancer progression from ductal carcinoma in situ (DCIS) to invasive cancer has grown rapidly. However, molecular factors driving the progression are still largely unknown. READ MORE

4. 2. Prognosis in carcinoma in situ of the breast

   Author : Fredrik Wärnberg; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Breast carcinoma; ductal carcinoma in situ; lobular carcinoma in situ; prognosis; histopathological grade; p53; c-erbB-2; Ki 67; Bcl-2; hormone receptors; angiogenesis; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

   Abstract : The incidence of breast cancer is rising steadily in Sweden and the proportion of carcinoma in situ (CIS) has increased appreciably, most likely due to mammography screening. The aim of this study was twofold: (1) to examine risk factors for subsequent invasive breast carcinoma and breast cancer death after primary ductal carcinoma in situ (DCIS) and (2) to study the biology in the progress between in situ and invasive carcinoma. READ MORE

5. 3. Molecular Pathogenesis of Cervical Carcinoma : Analysis of Clonality, HPV16 Sequence Variations and Loss of Heterozygosity

   Author : Xinrong Hu; Björn Hagmar; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; cervical carcinoma; CIN; HPV; LOH; X-chromosome inactivation; clonality; molecular pathogenesis; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

   Abstract : A previous model of morphological pathogenesis assumed that cervical carcinoma is of monoclonal origin and progresses through multiple steps from normal epithelium via CINS into invasive carcinomas. The aim of this study was to investigate the molecular mechanism of pathogenesis of cervical neoplasia. READ MORE

6. 4. MOLECULAR PROFILING OF UROTHELIAL CARCINOMA

   Author : David Lindgren; Avdelningen för klinisk genetik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cytogenetik; Urology; nephrology; Urologi; nefrologi; Clinical genetics; Klinisk genetik; cytogenetics; Genetics; cancer; onkologi; Cytologi; cancerology; oncology; Cytology; TP53; FGFR3; gene expression profiling; microarray; bladder cancer; urothelial carcinoma; Genetik;

   Abstract : The general aim of this thesis was to molecularly characterize urothelial carcinoma (UC) at the transcriptional level using gene expression microarrays to improve the classification and pathogenetic understanding of this disease. In the first two studies (Articles I and II), gene expression profiling was used to study dysregulated transcriptional networks in a large cohort of UCs. READ MORE

7. 5. Recurrent Non-Muscle-Invasive Bladder Cancer

   Author : Sigurdur Gudjonsson; Urologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; early instillation; biopsies; biomarkers; recurrence; bladder cancer; non-muscle-invasive; tissue microarray; gene-expression;

   Abstract : A characteristic feature of non-muscle-invasive bladder cancer (NMIBC) is the high risk of recurrent disease after primary treatment. Although only a minority of cases eventually progress to a life-threatening muscle-invasive tumour, it is necessary to conduct long-term follow-up with repeated cystoscopies. READ MORE