Search for dissertations about: "invasiveness"

Showing result 1 - 5 of 85 swedish dissertations containing the word invasiveness.

2. 1. Biotic resistance in freshwater fish communities

   Author : Anna Henriksson; Göran Englund; David Wardle A.; Jun Yu; Sebastian Diehl; Donald Jackson; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; biotic resistance; freshwater fish; introductions; invasions; invasion success; invasibility; invasiveness; species richness; saturation; species identity; weighted species richness;

   Abstract : Invasions of non-native species cause problems in ecosystems worldwide, and despite the extensive effort that has been put into research about invasions, we still lack a good understanding for why some, but not other, communities resist these invasions. In this doctoral thesis I test hypotheses on biotic resistance using a large dataset of more than 1000 both failed and successful introductions of freshwater fish into Swedish lakes. READ MORE

4. 2. Proteomics of invasiveness of human breast epithelial cells

   Author : Kah Wai Lin; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Mechanisms of malignant transformation and cancer invasion and factors controlling them in response to various stimuli remain elusive. We used proteomics and systems biology to explore these mechanisms in human breast epithelial cells. The objective has been to identify a set of biomarkers for diagnostics and prognostics of breast cancer. READ MORE

5. 3. Micro-environmental control of tumor differentiation and invasiveness

   Author : Caroline Gélabert; Aristidis Moustakas; Alexander Pietras; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; cell signaling; TGFβ; non-coding RNAs; metabolism;

   Abstract : The transforming growth factor β (TGFβ) family participates in embryonic development and adult tissue homeostasis. In early stages of tumorigenesis, TGFβ promotes cell cycle arrest and apoptosis; however, in advanced malignancies, TGFβ promotes tumor cell migration and metastasis via the induction of epithelial-tomesenchymal transition (EMT). READ MORE

6. 4. A Novel Approach for Radiotherapy and Radiosurgery Treatment Planning Accounting for High-Grade Glioma Invasiveness into Normal Tissue

   Author : Wille Häger; Iuliana Toma-Daşu; Marta Lazzeroni; Jesper Kallehauge; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Tumor modeling; medical physics; model; simulation; glioblastoma; gbm; medicinsk strålningsfysik; Medical Radiation Physics;

   Abstract : High-grade gliomas (HGGs) are a type of malignant brain cancer, which include glioblastomas (GBMs). In adults, GBM is the most common malignant primary brain cancer. Attempts to treat patients with GBMs have been conducted for over a century, but the prognosis has only marginally improved. READ MORE

7. 5. Molecular markers reflecting malignant transformation and tumor progression

   Author : Patricia Stoltzfus; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Molecular markers; interphase fluorescence in situ hytidization; genetic diagnostic test; laminin-5 gamma2 chain; immunohistochemistry; precancerous lesions; invasiveness; breast cancer; cervical squamous cell carcinoma; tongue carcinoma; vulvar carcinoma;

   Abstract : The early detection of neoplastic lesions is most critical in the successful treatment of malignant disease. This thesis investigates molecular targets for an improved detection and diagnosis of cancer by exploring the value of interphase fluorescence in situ hybridization (FISH) to detect specific chromosomal aneuploidies and gene amplifications, and laminin-5 gamma2 chain expression detected by immunohistochemistry as a marker for invasiveness. READ MORE