Search for dissertations about: "ion mass-spectrometry"

Showing result 1 - 5 of 223 swedish dissertations containing the words ion mass-spectrometry.

  2. 1. Liquid Chromatography Coupled to Mass Spectrometry : Implementation of Chemometric Optimization and Selected Applications

    Author : My Moberg; Jonas Bergquist; Karin E. Markides; Dan Bylund; Douglas B. Kell; Uppsala universitet; []
    Keywords : Analytical chemistry; liquid chromatography; mass spectrometry; tandem mass spectrometry; electrospray ionization; inductively coupled plasma; chemometrics; optimization; multivariate data analysis; design of experiments; response surface model; siderophore; azathioprine; peptide; Analytisk kemi;

    Abstract : Liquid chromatography (LC) coupled to mass spectrometry (MS) offers highly selective and sensitive analysis of a wide variety of compounds. However, the use of hyphenated experimental set-ups implies that many parameters may have an effect on the studied response. READ MORE

  4. 2. Novel strategies to increase throughput and differentiate lipid isomers in mass spectrometry imaging : Development of computational tools and complex mass spectrometric methods for nanospray desorption electrospray ionization

    Author : Johan Lillja; Ingela Lanekoff; Daniel Globisch; Orešič Matej; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mass spectrometry; Mass spectrometry imaging; Tandem mass spectrometry; Silver cationization; Mathematical modeling; Lipid; Lipid isomer; Kemi med inriktning mot analytisk kemi; Chemistry with specialization in Analytical Chemistry;

    Abstract : In this thesis, method development for improved analyte identification and throughput in mass spectrometry imaging (MSI) is discussed. In MSI, the spatial distribution of analytes from a sample is determined and visualized, information about the detected molecules interaction within the sample can thereby the deduced. READ MORE

  5. 3. New Materials and Improved Ambient Techniques in Mass Spectrometry

    Author : Nicolò Riboni; Leopold Ilag; Elisa Robotti; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mass Spectrometry; Solid Phase Microextraction; Ambient Mass Spectrometry; Desorption Electrospray Ionization; Paper Spray Ionization; Cavitands; BTEX; New Psychoactive Substances; Analytical Chemistry; analytisk kemi;

    Abstract : Mass spectrometry (MS) is used in several fields, e.g. biology, environmental monitoring, medicine and forensics due to excellent qualitative and quantitative capabilities. The development of new instrumental setups and ionization sources is crucial to analyze a variety of compounds at trace levels. READ MORE

  6. 4. Chiral Recognition by Means of Mass Spectrometry

    Author : Oleksii Rebrov; Mats Larsson; Per Johnsson; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Chirality; Mass spectrometry; Chiral recognition; Gas phase; kemisk fysik; Chemical Physics;

    Abstract : This thesis is based on experimental studies of chiral ions in gas-phase. Electrospray ion source platform (Stockholm University) and commercially available Quadrupole Time-of-Flight mass spectrometer have been used in our studies. READ MORE

  7. 5. Secondary and Higher Order Structural Characterization of Peptides and Proteins by Mass Spectrometry

    Author : Christopher Adams; Roman Zubarev; Göran Possnert; Carlito Lebrilla; Uppsala universitet; []
    Keywords : Engineering physics; Protein Structure; Mass Spectrometry; Electron Capture Dissociation; Tandem Mass Spectrometry; Teknisk fysik;

    Abstract : The work in this thesis has demonstrated the advantages and limitations of using MS based technologies in protein and peptide structural studies. Tandem MS, specifically electron capture dissociation (ECD) have shown the ability to provide structural insights in molecules containing the slightest of all modifications (D-AA substitution). READ MORE