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Showing result 1 - 5 of 121 swedish dissertations matching the above criteria.
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1. Intestinal ischemia and reperfusion. Proinflammatory response and organ dysfunction
Abstract : Intestinal I/R is considered to be an important initiating event in several pathophysiological conditions such as trauma, bleeding, sepsis and pancreatitis, frequently leading to concomitant both single and potentially multiple organ dysfunction. The purpose of this thesis was to study mechanims underlying the development of multiple organ dysfunction, with special focus on intercellular proinflammatory regulation in the concurrent development of tissue injury. READ MORE
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2. Improved bioenergetic recovery during experimental ischemia and reperfusion by irradiation
Abstract : Prolonged ischemia and reperfusion frequently occur during clinical operations. The bioenergetic status decreases during ischemia and reactive oxygen species (ROS) are formed during reperfusion, which may lead to irreversible tissue injury. READ MORE
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3. Hyperglycemia and Focal Brain Ischemia : Clinical and Experimental Studies
Abstract : Diabetes is a major risk factor for ischemic stroke and is associated with increased mortality. Additionally, hyperglycemia, a common complication in acute stroke, is associated with poor outcome. READ MORE
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4. Energy metabolism in skeletal muscle during ischemia and reperfusion. Experimental and clinical aspects
Abstract : Microsurgical operations, using free vascularised transfer of tissues, induce an obligatory period of ischemia followed by reperfusion. The degree of ischemia and reperfusion injury is dependent on the ischemia time. READ MORE
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5. Renal Ischemia/Reperfusion Injury in Diabetes : Experimental Studies in the Rat
Abstract : Diabetes mellitus (DM) is one of the leading causes of end stage renal failure. An increased susceptibility to renal ischemia/reperfusion (I/R)-injury was found in DM rats. Unilateral renal ischemia for as short as 20 minutes led to an irreversible progressive injury in DM kidneys, whereas the injury in non-DM kidneys was almost reversible. READ MORE