Search for dissertations about: "islet amyloid polypeptide"

Showing result 16 - 20 of 21 swedish dissertations containing the words islet amyloid polypeptide.

  2. 16. Expression of Islet Amyloid Polypeptide - Localization and regulation in the pancreatic islets, gastrointestinal tract and sensory nervous system

    Author : Hindrik Mulder; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sekretion; Endokrinologi; diabetologi; Endocrinology; secreting systems; diabetology;

    Abstract : Islet amyloid polypeptide (IAPP; also named ”amylin”) is a member of the calcitonin superfamily of peptides, displaying the closest structural relationship to the neuropeptide calcitonin gene-related peptide (CGRP). It is expressed in islet beta-cells and forms islet amyloid in type 2 diabetic patients. READ MORE

  4. 17. Glucose metabolism in patients with exocrine pancreatic adenocarcinoma

    Author : Johan Permert; Linköpings universitet; []
    Keywords : endocrine pancreatic function; euglycemic hyperinsulinemic clamp; exocrine pancreatic adenocarcinoma; glucose metabolism; glyccogen synthesis; hyperglycemic clamp; immunohistochemistry; insulin resistance; insulin secretion; in situ hybridization; islet amuyloid polypeptide IAPP ; radioimmunoassay; subtotal pancreatectomy; MEDICINE; MEDICIN;

    Abstract : Carc.inoma of the exocrine pancreas is the fifth leading cause of cancer death in the Western world and the survival rate is one of the lowest for cancers of any site. Pancreatic cancer is characterized by pronounced, early cachexia and frequent metabolic complications. READ MORE

  5. 18. Studies of amyloid toxicity in Drosophila models and effects of the BRICHOS domain

    Author : Erik Hermansson Wik; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Amyloid diseases involve specific protein misfolding events and formation of fibrillar deposits. The symptoms of these diseases are broad and dependent on site of accumulation, with different amyloid proteins depositing in specific tissues or systematically. READ MORE

  6. 19. Electron tomography analysis of 3D order and interfacial structure in nano-precipitates

    Author : Ling Xie; Klaus Leifer; Christian Kübel; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Electron tomography; nanoprecipitate; interfacial structure.; Materialvetenskap; Materials Science;

    Abstract : Structural characterization is essential to understand the formation mechanisms of the nanostructures in thin absorber layers in third generation solar cells and amyloid protein aggregates. Since to the dimension of the precipitated structures is in nanometer scale, electron tomography technique in transmission electron microscopy (TEM) has been applied as a major tool to analyze the 3D order and distribution of precipitates using the electron tomography technique. READ MORE

  7. 20. The type IV Oligodendrocyte : experimental studies on chicken white matter

    Author : Emma S. Anderson; Arthur M. Butt; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : In mammals, islet amyloid polypeptide (IAPP) is co-produced with insulin in pancreatic ß-cells. In the chicken, the expression of IAPP in the brain is more than 10-fold higher than in the pancreas. READ MORE