Search for dissertations about: "islet revascularization"
Showing result 1 - 5 of 15 swedish dissertations containing the words islet revascularization.
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1. Formation of Composite Islet Grafts : A novel strategy to promote islet survival and revascularization
Abstract : The islets of Langerhans are small and delicate spheroid organs scattered in the pancreas responsible for insulin production. Transplantation of isolated islets is a beneficial therapy for patients with a severe form of type 1 diabetes. READ MORE
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2. Pancreatic Islet Transplantation : Modifications of Islet Properties to Improve Graft Survival
Abstract : During the past decade clinical islet transplantation has become a viable strategy for curing type 1 diabetes. The limited supply of organs, together with the requirement for islets from multiple donors to achieve insulin independence, has greatly limited the application of this approach. READ MORE
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3. The Microvasculature of Endogenous and Transplanted Pancreatic Islets : Blood Perfusion, Oxygenation and Islet Endocrine Function
Abstract : Type 1 diabetes mellitus affects millions of people worldwide. Islet transplantation is a minimal invasive surgical procedure that restores euglycemia and halts the progression of diabetic complications. However, despite transplantation of islets from multiple donors most patients reverse to hyperglycemia within five years. READ MORE
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4. In vivo imaging of islet cells and islet revascularization
Abstract : Glucose homeostasis depends on the release of insulin from the pancreatic beta-cell. Impaired insulin release is a hallmark of diabetes mellitus. READ MORE
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5. Implantation-Site Dependent Differences in Engraftment and Function of Transplanted Pancreatic Islets
Abstract : Transplanting pancreatic islets into the liver through the portal vein is currently the most common procedure in clinical islet transplantations for treating patients with brittle type 1 diabetes. However, most islet grafts fail within a 5-year period necessitating retransplantation. READ MORE