Search for dissertations about: "isoprostane"

Showing result 1 - 5 of 11 swedish dissertations containing the word isoprostane.

  2. 1. Experimental cardiopulmonary cerebral resuscitation : A study of cerebral perfusion with special reference to the postresuscitation disturbances

    Author : Ala Nozari; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Cardiac arrest; cardiopulmonary resuscitation; cerebral blood flow; post-resuscitation period; epinephrine; vasopressin; aortic occlusion; isoprostane; Kirurgi; Surgery; Kirurgi; Anestesiologi; Anaesthesiology;

    Abstract : Ischemic neuronal injury continues to be a major delimiting factor in achieving successful clinical outcomesafter resuscitation from cardiac arrest. In this thesis, a pig model of cardiopulmonary resuscitation (CPR) wasused to address the effects of different interventions on cerebral blood flow and oxygenation during CPR and theinitial postresuscitation period. READ MORE

  4. 2. Determination of biomarkers for lipid peroxidation and oxidative stress : Development of analytical techniques and methods

    Author : Kristina Claeson Bohnstedt; Bo Karlberg; Niels Heegaard; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; capillary electrophoresis; mass spectrometry; electrospray; porous graphitic carbon; oxidative stress; lipid peroxidation; biomarker; malondialdehyde; hydroxynonenal; isoprostane; Analytical chemistry; Analytisk kemi;

    Abstract : Oxidative stress can be defined as a state of disturbance in the pro-oxidant/antioxidant balance in favour of the former, leading to potential damage. Processes associated with oxidative stress involve reactive oxygen species and radicals and can result in elevated levels of oxidatively modified or toxic molecules that can cause cellular malfunction, and even cell death. READ MORE

  5. 3. Biochemical and Epidemiological Studies of Early-Onset and Late-Onset Pre-Eclampsia

    Author : Anna-Karin Wikström; Matts Olovsson; Ulf Eriksson; Solveig Norden-Lindeberg; Göran Berg; Uppsala universitet; []
    Keywords : Obstetrics and gynaecology; pre-eclampsia; proteinuria; albumin-creatinine ratio; ischaemic heart disease; angiogenesis; sFlt1; oxidative stress; isoprostane; PAI-1; PAI-2; Obstetrik och kvinnosjukdomar;

    Abstract : Biochemical and epidemiological aspects of pre-eclampsia were investigated, with the main focus on possible pathophysiological differences between early-onset and late-onset disease.In pre-eclamptic women poor correlation was found between albumin-creatinine ratio (ACR) in a random urine sample and total amount of albumin in a 24-hour urine collection. READ MORE

  6. 4. Prostaglandins and Isoprostanes in Relation to Risk Factors for Atherosclerosis : Role of Inflammation and Oxidative Stress

    Author : Johanna Helmersson; Samar Basu; Bengt Vessby; Tommy Cederholm; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Public health; prostaglandin F2α; F2-isoprostane; interleukin-6; C-reactive protein; serum amyloid A; tocopherols; cardiovascular risk factors; variation; inflammation; oxidative stress; human; Folkhälsomedicin; Public health medicine research areas; Folkhälsomedicinska forskningsområden;

    Abstract : Inflammation and oxidative stress may be involved in atherogenesis. This thesis describes clinical studies of prostaglandin F2α (PGF2α), an inflammatory mediator, and the isoprostane 8-iso-PGF2α, a reliable indicator of oxidative stress, and cytokine-related inflammatory mediators and indicators in healthy subjects and in a population-based cohort of Swedish men. READ MORE

  7. 5. Milk Fat Intake and Conjugated Linoleic Acid (CLA) Supplementation : Dietary Markers and Associations to Clinical and Biochemical Characteristics

    Author : Annika Smedman; Samar Basu; Bengt Vessby; Jan I Pedersen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nutrition; Pentadecanoic acid 15:0 ; milk products; milk fat; dietary marker; coronary heart disease; anthropometric variables; conjugated linoleic acid CLA ; lipid peroxidation; inflammation; F2 isoprostane; prostaglandin F2; human; Näringslära; Nutrition; Näringslära;

    Abstract : In the present thesis dietary markers for intake of milk fat, associations between intake of milk fat and risk factors for coronary heart disease (CHD), and the effects of supplementation with conjugated linoleic acid (CLA) to healthy humans are investigated.The dietary fat quality is one of the main lifestyle factors affecting risk for CHD. READ MORE