Search for dissertations about: "isoproterenol"

Showing result 1 - 5 of 11 swedish dissertations containing the word isoproterenol.

2. 1. Functional significance of phosphorylation of rat renal Na+, K+-ATPase by PKA and PKC

   Author : Sam Xian Jun Cheng; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Na ; K -ATPase; protein phosphorylation; cAMP-dependent protein kinase; protein kinase C; site-directed mutagenesis; DNA transfection; isoproterenol; [Ca2 ]i.;

   Abstract : The activity of Na+,K+-ATPase (NKA) is short term regulated by hormones as well as by signalling pathways that involve activation of PKA or PKC, but the mechanism(s) remains unclear. This study was performed to evaluate whether this regulation of NKA occurs via PKA- or PKC-mediated phosphorylation of the NKA a subunit. READ MORE

4. 2. Cyclic Nucleotide Phosphodiesterase 3B: Regulation in rat adipocytes and 3T3-L1 cells

   Author : Tova Landström; Institutionen för experimentell medicinsk vetenskap; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 3T3-L1 TNF-alpha; adipocyte; insulin; p70S6 kinase; mitogen-activated protein kinase; protein kinase B; phosphatidylinositol-3 kinase; phosphodiesterase 3B; cAMP; lipolysis; phosphorylation; signal transduction; Biochemistry; Metabolism; Biokemi; metabolism;

   Abstract : Insulin stimulation of rat adipocytes results in phosphorylation and activation of the cyclic nucleotide phosphodiesterase 3B (PDE3B), a key enzyme in the antilipolytic signalling pathway of this hormone. In this thesis, the site phosphorylated in PDE3B upon stimulation of rat adipocytes with insulin and/or the beta-adrenergic agonist, isoproterenol is identified. READ MORE

5. 3. Expanding role of caveolae in control of adipocyte metabolism : proteomics of caveolae

   Author : Nabila Aboulaich; Peter Strålfors; Alexander Vener; Hans Jörnvall; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Diabetes; Insulin signalling; Fatty acid metabolism; Proteomics; Mass spectrometry; Cell and molecular biology; Cell- och molekylärbiologi;

   Abstract : The primary function of adipose tissue is to store energy in the form of triacylglycerol, which is hydrolyzed to fatty acids to supply other tissues with energy. While insulin promotes the storage of triacylglycerol, catecholamines stimulate its hydrolysis. READ MORE

6. 4. Insulin Signalling in Human Adipocytes and its Interplay with beta-Adrenergic Control of Lipolysis

   Author : Cecilia Karlsson; Peter Strålfors; Maria V Turkina; Jan Eriksson; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Abstract : The prevalence of obesity has over the last 40 years nearly tripled and obesity is one of the major risk factors of developing type 2 diabetes. Type 2 diabetes was formerly called adultonset diabetes but today, probably due to the rise in childhood obesity, it is also seen in children and adolescents. READ MORE

7. 5. Sleep disordered breathing and hemodynamic function

   Author : Ludger Grote; Göteborgs universitet; []
   Keywords : sleep apnea; hypertension; blood pressure; vascular function; exercise; arousal;

   Abstract : This thesis addresses the association between sleep disordered breathing (SDB) and hemodynamic function. A cross sectional study in a sleep laboratory cohort (n=1190) demonstrated a dose-response relationship between the severity of SDB, expressed as respiratory disturbance index (RDI), and office blood pressure, heart rate, and the risk of hypertension. READ MORE