Search for dissertations about: "isoquinoline"

Found 5 swedish dissertations containing the word isoquinoline.

  2. 1. Transition Metal Mediated Transformations of Carboranes

    Author : Ludvig Eriksson; Kalman Szabo; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Chemistry; carborane; isoquinoline; PK11195; peripheral bensodiazepine receptor; Cu I Iodide; iodinated carborane; palladium; isotopic exchange; Herrmann’s Catalyst; Heck reaction; Suzuki-Miyaura reaction; cross coupling; arylation; olefination; 125-iodine; radiolabelling; carboraneboronic ester; BNCT; 2-iodo-; Kemi; Chemistry; Kemi; organisk kemi; Organic Chemistry;

    Abstract : This thesis describes the use of copper and palladium to mediate transformations of carboranes, especially p-carborane.1-(1-p-carboranyl)-N-methyl-N-(2-butyl)-3-isoquinolinecarboxamide, a carborane containing analogue of the peripheral benzodiazepine receptor (PBR) ligand PK11195, has been synthesised. READ MORE

  4. 2. Synthesis of biomolecules for nuclide therapy : Studies on amino acids, nucleosides and isoquinolines

    Author : Charlottta Naeslund; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Chemistry; Kemi; Chemistry; Kemi; organisk kemi; Organic Chemistry;

    Abstract : Nuclide therapy for cancer is based on the selective delivery of nuclide bearing compounds to tumour cells. Radionuclides, such as 125I, may be used, as well as stable isotopes, such as 10B, which is activated on site by an external neutron source. READ MORE

  5. 3. Radiohalogenation of biomolecules : An experimental study on radiohalogen preparation, precursor synthesis, radiolabeling and biodistribution

    Author : Jacek Koziorowski; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Chemistry; Kemi; Chemistry; Kemi; organisk kemi; Organic Chemistry;

    Abstract : Radiohalogens are widely used in nuclear medicine, both as tool for diagnostic in vivo imaging and inradionuclide therapy. This study deals with the use of radiohalogens; separation, precursor synthesis, labeling and biological behavior. READ MORE

  6. 4. [11C]Carbon Monoxide and Aryl Triflates in Palladium-Mediated Carbonylation Reactions : Synthetic approaches to [11C]Carbonyl Compounds and [11C]Amines

    Author : Obaidur Rahman; Bengt Långström; Fredrik Almqvist; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; [11C]Carbon monoxide; Aryl triflates; Carbonylation; Organisk kemi; Organic chemistry; Organisk kemi;

    Abstract : The usefulness of low concentrations (typically 10 to 100 µM) of [11C]carbon monoxide and aryl triflates as substrates in 11C-carbonylation using different nucleophiles in the presence of lithium bromide was investigated. The reactions were performed in a micro autoclave of 200 µL volume and catalysed (mediated) by palladium(0). READ MORE

  7. 5. Elicitor-induced formation of secondary products in plant cell cultures. Production of benzophenanthridine alkaloids in Eschscholtzia californica Cham. and hydroxycinnamic acid tyramides in Nicotiana glutinosa L

    Author : Mirza Villegas; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; macarpine; chelerythrine; sanguinarine; benzophenanthridine alkaloids; Nicotiana glutinosa; Eschscholtzia californica; secondary metabolites; Key words elicitors; immobilisation; hydroxycinnamoyltyramides.; Plant biochemistry; Växtbiokemi;

    Abstract : Biotic and abiotic elicitors induce biosynthesis of secondary metabolites (phytoalexins) as a defense against pathogenic organisms in plants. The use of cell suspension cultures in combination with elicitors offer excellent experimental model systems for studies on various elicitor-induced responses of plant tissues. READ MORE