Search for dissertations about: "jakob domert"

Found 1 swedish dissertation containing the words jakob domert.

2. 1. Neuron-to-neuron propagation of neurodegenerative proteins; relation to degradative systems

   Author : Jakob Domert; Martin Hallbeck; Jan Marcusson; Lars Tjernberg; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell-to-cell transfer; beta-amyloid; Alzheimer s disease; degradation; proteasome; alpha-synuclein; Parkinson s disease; high throughput screening model;

   Abstract : Alzheimer’s disease (AD) and Parkinson’s disease (PD) are defined by neurodegeneration and accumulations of misfolded proteins that spread through the brain in a well characterized manner. In AD these accumulations consist mainly of β-amyloid (Aβ) and tau, while in PD, α-synuclein (α-syn) make up the characteristic lewy pathology. READ MORE