Search for dissertations about: "jones"

Showing result 1 - 5 of 116 swedish dissertations containing the word jones.

  1. 1. Targeting Infectious Disease : Structural and functional studies of proteins from two RNA viruses and Mycobacterium tuberculosis

    Author : Anna M. Jansson; T. Alwyn Jones; Sherry L. Mowbray; E. Yvonne Jones; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; RNA virus; coronavirus; alphacoronavirus; nsp1; TGEV; flavivirus; Modoc virus; NS5; methyltransferase; mRNA capping; Mycobacterium tuberculosis; tuberculosis; 1-deoxy-D-xylulose 5-phosphate reductoisomerase; DXR; fosmidomycin analogues; MEP pathway; drug development; xray-crystallography; Biology with specialization in Structural Biology; Biologi med inriktning mot strukturbiologi; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi; Biokemi; Biochemistry; Medicinal Chemistry; Läkemedelskemi;

    Abstract : The recent emergence of a number of new viral diseases as well as the re-emergence of tuberculosis (TB), indicate an urgent need for new drugs against viral and bacterial infections.Coronavirus nsp1 has been shown to induce suppression of host gene expression and interfere with host immune response. READ MORE

  2. 2. Non-coding RNAs in beta cell insulin secretion - emerging players in Type 2 Diabetes pathogenesis

    Author : Jones Ofori; Diabetes - öcellsexocytos; []
    Keywords : T2D; insulin secretion; exocytosis; ncRNAs; GAS5; miR-152; miR-335; miR-130a b; miR-375; STXBP1; SNAP25; SYT13; PDHA1; PDX1; glucocortiocoid; beta cell function; glucose metabolism;

    Abstract : Type 2 diabetes (T2D) is a complex polygenic disease influenced by both environmental and genetic factors resulting in impaired insulin release from pancreatic beta cells and insulin resistance in target tissues. The incidence of T2D is escalating and it is projected that over 640 million people will be affected by 2040. READ MORE

  3. 3. Birch Stem and Wood Traits in Genetic and Silviculture Trials in Southern Sweden

    Author : Grace Jones; Stergios Adamopoulos; Mateusz Liziniewicz; Mikael Andersson; Sheikh Ali Ahmed; Erkki Verkasalo; Linnéuniversitetet; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; acoustic velocity; Betula spp.; dynamic MOE; genetic parameters; grain angle; hardwood; Itrax densitometry; mixed forests; non-destructive testing; stem form; akustisk velocitet; Betula spp.; blandskog; densitometri; genetiska parametrar; icke destruktiva metoder; Itrax; lövträ; skogsodling; stamkvalitet; vedsegenskaper; Forestry and Wood Technology; Skog och träteknik;

    Abstract : Swedish tree species of birch (silver: Betula pendula and downy: B. pubescens) are often neglected during forest management activities, resulting in low value logs. This thesis investigated birch stem characteristics and wood properties important for solid wood products, in genetics and management trials in southern Sweden. READ MORE

  4. 4. Denitrification: from genes to ecosystems

    Author : Christopher Jones; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Denitrification is a part of the global nitrogen cycle in which fixed nitrogen in the biosphere is returned to the atmosphere, which is mediated by diverse communities of microorganisms. This thesis seeks to gain a greater understanding of the ecology of denitrifying microorganisms by examining the pathway from four different aspects; gene, population, community, and ecosystem. READ MORE

  5. 5. Formation of small molecules in space through the process of radiative association

    Author : Daria Jones; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; astrochemistry; reaction rate constants; formation of molecules; physical chemistry;

    Abstract : This thesis is dedicated to calculating the reaction rate constants for the formation of molecules through radiative association (RA) under interstellar conditions. The molecules that have been studied are CH, AlCl, Na+ − H2 and Al+ − H2. READ MORE