Search for dissertations about: "kainic acid"

Showing result 1 - 5 of 24 swedish dissertations containing the words kainic acid.

  2. 1. Anti-Apoptotic Proteins in Nerve Cell Survival and Neurodegeneration

    Author : Laura Korhonen; Marja Jäättelä; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; neuronal cell death; XIAP; RIAP-2; Hippocalcin; Bcl-2; Bcl-X; kainic acid; DRG; estrogen; Neurovetenskap; Neurology; Neurologi; Developmental Neurosciences; medicinsk utvecklings- och neurobiologi;

    Abstract : Apoptosis is a genetically regulated cell death program, which shows distinct morphological characteristics. It takes place during neuronal development and in some neurodegenerative diseases. During apoptosis, the intracellular proteins are degraded by various caspases, cysteine aspartases, which are regulated by pro- and anti-apoptotic signals. READ MORE

  4. 2. Role of intermediate filaments and expression of GFAP and S-100 in astrocytes

    Author : Mei Ding; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Astrocytes; Gliosis; Kainic acid; Transgenic mouse; S-100; GFAP; Vimentin; RVD regulatory volume decrease ; Taurine; Glutamine; Ascorbate; Glucose;

    Abstract : Astrocytes participate in a variety of important physiologic and pathologic processes in the central nervous system (CNS). One of the most remarkable characteristics of astrocytes is their vigorous response to CNS injuries. READ MORE

  5. 3. On the neuropeptide mRNA expression following neuropsychopharmacological treatments

    Author : Olof Zachrisson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Cholecystokinin; Excitotoxicity; Electroconvulsive; In situ hybridisation; Kainic acid; Lithium; Manic-depressive illness; Neuropeptide Y; Rat brain; Schizophrenia; Seizure; Somatostatin; Substance P; Tachykinin receptor;

    Abstract : In addition to classical neurotransmitters, an increasing number of neuropeptides have been found in the brain. Although neuropeptides may play important roles especially in higher brain functions such as emotion, mood, memory, and learning, most focus has been directed upon classical neurotransmitters and their receptors. READ MORE

  6. 4. NR4A orphan nuclear receptors in immediate early regulation of retinoid signaling and neuroprotection

    Author : Nikolaos Volakakis; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : NR4A receptors show distinct properties that make them unique within the family of nuclear receptors. They lack a ligand-binding cavity and a canonical coactivator-binding site and they are induced both in vivo and in vitro in an immediate early way by an extremely wide repertoire of substances/conditions. READ MORE

  7. 5. Region-specific expression of the interleukin-1 system in rat brain following endotoxin challenge and excitotoxic neurodegeneration

    Author : Charlotta Eriksson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Traditionally, up-regulation and secretion of cytokines are associated with peripheral immune and inflammatory responses. There is now evidence that cytokines also exert various actions in the central nervous system (CNS). READ MORE