Search for dissertations about: "keratinocyte"

Showing result 21 - 25 of 48 swedish dissertations containing the word keratinocyte.

  2. 21. Dysregulation of receptor induced apoptosis during human leishmaniasis : a possible mechanism of skin ulceration

    Author : Liv Eidsmo; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Cutaneous leishmaniasis; visceral leishmaniasis; Death Receptors; Fas; FasL; Apoptosis;

    Abstract : Leishmaniasis is endemic in 88 countries and 12 million people per year have been estimated to be at risk of infection. The causative agent, the protozoan Leishmania, is spread by sand-flies and infects macrophages in the mammalian host. Leishmaniasis in humans form a spectrum of clinical presentations. In cutaneous leishmaniasis (CL) caused by L. READ MORE

  4. 22. Studies on molecular regulation of inflammation in cutaneous lupus erythematosus

    Author : Vilija Oke; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Lupus erythematosus (LE) is an autoimmune disease with a wide range of clinical manifestations. This spectrum spans from limited cutaneous disease to life-threatening rheumatic disorder involving vital organs. Sun exposure is an evident exogenous trigger of both cutaneous (CLE) and systemic LE (SLE). READ MORE

  5. 23. Cobalt in the hard metal production industry : exposure via inhalation and skin and the inflammatory response in human keratinocytes

    Author : Maria Klasson; Eva Särndahl; Håkan Westberg; Magnus Lindberg; Alexander Persson; Kristina Jakobsson; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cobalt; cobalt chloride; skin; HaCaT; in vitro; cell viability; pro-inflammatory cytokines; NLRP3 inflammasome;

    Abstract : Cobalt is a strong sensitizer and can cause contact allergy upon both direct contact or from airborne exposure on the skin. In the skin, keratinocytes are the first cells to come in contact with the metal and will react and respond to the danger by triggering an alarm system resulting in an inflammatory response in the skin. READ MORE

  6. 24. Psoriasis : from transcriptome to miRNA function and biomarkers

    Author : Lorenzo Pasquali; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Psoriasis is a chronic inflammatory, immune-mediated skin condition that affects in average 2 to 3% of the world population, phenotypically characterized by red and scaly plaques on the skin of affected patients. It is a multifactorial disorder, in which both genetic predisposition and environment play key roles. READ MORE

  7. 25. Plasminogen : a novel inflammatory regulator that promotes wound healing

    Author : Yue Shen; Tor Ny; Gunilla Høyer-Hansen; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Plasminogen; inflammation; wound healing; diabetic wounds; tympanic membrane perforations; medicinsk biokemi; Medical Biochemistry;

    Abstract : The plasminogen activator (PA) system has been shown to be intimately involved in wound healing. However, the role of this system in the initiation and resolution of inflammation during healing process remained to be determined. READ MORE