Search for dissertations about: "keratopathy"

Showing result 1 - 5 of 6 swedish dissertations containing the word keratopathy.

  1. 1. Aniridia-related keratopathy : structural changes, signaling pathways and clinical aspects

    Author : André Vicente; Fatima Pedrosa Domellöf; Berit Byström; Luis Abegão Pinto; Jing-Xia Liu; Anders Ivarsen; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; aniridia; aniridia-related keratopathy; PAX6; keratoplasty; fetal cornea; Notch1; Wnt; sonic hedgehog; mTOR; keratocyte; oftalmiatrik; ophthalmology;

    Abstract : Aniridia is a congenital autosomal dominant, bilateral, panocular condition, caused by haploinsufficiency of the Pax6 transcription factor. Aniridia-related keratopathy (ARK) significantly affects vision and quality of life in these patients. READ MORE

  2. 2. Corneal transplant outcome- a Swedish register

    Author : Margareta Claesson; Göteborgs universitet; []
    Keywords : Corneal transplantation; Quality register; Long term follow up; Astigmatism; Bullous keratopathy; Graft survival; Visual outcome;

    Abstract : Aim. The aim of this study was to present different aspects of the outcome after corneal transplantation based on data from the Swedish Cornea Register. Papers. The first paper describes the register and gives descriptive statistics and analysis of data from a two-year follow up, while the last paper presents data from a ten-year follow up. READ MORE

  3. 3. Immunological and inflammatory mechanisms in ocular allergy with special reference to vernal keratoconjunctivitis : clinical and experimental studies

    Author : Per Montan; Karolinska Institutet; Karolinska Institutet; []
    Keywords : allergic conjunctivitis; allergen challenge; atopy; conjunctival biopsy; eosinophils; ECP; IgE; immunohistochemistry; inflammation; interleukins; T-cells; tears; vernal keratoconjunctivitis;

    Abstract : Ocular allergy encompasses a wide range of conditions, most of which implicate IgE in the pathogenesis. In contrast to the benign nature of seasonal allergic conjunctivitis (SAC), the less common chronic eye diseases vernal and atopic keratoconjunctivitis (VKC and AKC) are severe and debilitating disorders. READ MORE

  4. 4. Ultraviolet radiation and cornea

    Author : Alexander Podskochy; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Cornea; UVR; keratocytes; apoptosis; Fas ligand; hyaluronan; biglycan; rabbit; wound healing.;

    Abstract : Background: Acute exposure of the mammalian eye to UVR results in development of photokeratitis after a period of a few hours. Chronic exposure to UVR is associated with an increased risk of several corneal disorders, including pterygium, climatic droplet keratopathy, and climatic proteoglycan stromal keratopathy. READ MORE

  5. 5. On Aniridia in Sweden and Norway

    Author : Ulla Edén; Lund Oftalmologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gillespie syndrome; Aniridia; PAX6 gene;

    Abstract : Introduction Aniridia (iris more or less missing), is a congenital, dominant, inherited, serious and sight-threatening disease, most often appearing as an isolated eye disorder. It is caused by mutations in the PAX6 gene, the master gene of the development of the eye. Typically, Aniridia causes severe visual impairment. READ MORE