Search for dissertations about: "kinase characterization"

Showing result 1 - 5 of 92 swedish dissertations containing the words kinase characterization.

  1. 1. Human Aquaporins: Production, Characterization and Interactions

    Author : Jennie Sjöhamn; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; aquaporins; membrane protein; protein production; protein characterization; protein:protein interactions; structural biochemistry;

    Abstract : Membrane proteins are essential components of the cell and responsible for the communication with the outside environment and transport of molecules across the membrane. Water transport is facilitated by aquaporins, which are water selective transmembrane pores that serve to maintain cell homeostasis. READ MORE

  2. 2. Mechanistic Implications and Characterization of Anaplastic Lymphoma Kinase (ALK) mutations in Neuroblastoma

    Author : Damini Chand; Bengt Hallberg; Christer Larsson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuroblastoma; ALK; crizotinib; receptor tyrosine kinase; molekylärbiologi; Molecular Biology;

    Abstract : Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase that was first reported as a fusion partner of nucleophosmin in Anaplastic large cell lymphoma in 1994. ALK is involved in myriad of cancers including neuroblastoma which is the most common extracranial solid tumor affecting young children. READ MORE

  3. 3. Molecular characterization of protein phosphorylation in plant photosynthetic membranes

    Author : Maria Hansson; Alexander V. Vener; Jean-David Rochaix; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; protein phosphorylation; photosynthesis; mass spectrometry; protein characterization; Cell biology; Cellbiologi;

    Abstract : Higher plants cannot move to a more favorable place when the environmental conditions are changing. To adapt to changes in light, temperature and access to water the plants had to evolve special mechanisms at the molecular level. READ MORE

  4. 4. Hormone-Sensitive Lipase and Protein Kinase B; Molecular characterization in testis, adipose tissue and pancreatic beta cells

    Author : Lena Stenson; Signaltransduktionsforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; signal transduction; pancreas; beta cells; adipocyte; insulin; Akt; protein kinase B; spermatogenesis; cholesterol esterase; hormone-sensitive lipase; testis; cAMP; Proteins; enzymology; Proteiner; enzymologi;

    Abstract : Hormone-sensitive lipase (HSL) and protein kinase B (PKB) are enzymes that in different ways are associated with lipid metabolism. While HSL is the well-known lipolytic enzyme responsible for hydrolysis of stored triacylglycerols in adipose tissue, PKB is a recently identified serine/threonine protein kinase, ubiquitously expressed and involved in signal transduction pathways induced by insulin and growth factors. READ MORE

  5. 5. Novel Insight into Thymidylate Kinase: Biochemical Characterization of the Human and Zebrafish Enzymes

    Author : Jun Mei Hu Frisk; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Deoxythymidine triphosphate (dTTP or T) is one of the four building blocks for DNA. In dTTP synthesis, the catalysis of dTMP to dTDP, is mediated by one known enzyme only: Thymidylate kinase (TMPK, EC 2.7.4. READ MORE