Search for dissertations about: "klass"

Showing result 6 - 10 of 152 swedish dissertations containing the word klass.

  2. 6. Versatile Implementations of an Improved Cell-Free System for Protein Biosynthesis : Functional and structural studies of ribosomal protein L11 and class II release factor RF3. Novel biotechnological approach for continuous protein biosynthesis

    Author : Lamine Bouakaz; Måns Ehrenberg; Richard Buckingham; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Protein synthesis; translation termination; ribosome; release factor; cell-free system; missense error; gel filtration; affinity chromatography; Molekylärbiologi; Molecular biology; Molekylärbiologi;

    Abstract : Advances in genetics, proteomics and chromatography techniques have enabled the successfully generation of a cell-free bacterial translation system composed of highly pure and active components. This system provided an ideal platform for better elucidating the mechanism of each individual step of the prokaryotic protein biosynthesis and the function of the translation factors involved in the process. READ MORE

  4. 7. The quality control of MHC class I antigen presentation

    Author : Kajsa M Paulsson; Antigen presentation; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chaperone; assembly; COPI; antigenic peptide; TAP; MHC; tapasin; Immunology; serology; transplantation; Immunologi; serologi;

    Abstract : Major histocompatibility complex (MHC) class I molecules present antigenic peptides to CD8+ T cells. The peptides are generated by proteasomes in the cytosol, then translocated across the membrane of the endoplasmic reticulum (ER) by the transporter associated with antigen processing (TAP). READ MORE

  5. 8. The evolution of ribonucleotide reductases

    Author : Daniel Lundin; Anthony Poole; Britt-Marie Sjöberg; Christos Ouzounis; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Evolution; ribonucleotide reductase; horizontal gene transfer; phylogeny; protein classification; Molecular biology; Molekylärbiologi; Molecular Biology; molekylärbiologi;

    Abstract : Ribonucleotide reductase (RNR) catalyses the transformation of RNA building blocks, ribonucleotides, to DNA building blocks, deoxyribonucleotides. This is the only extant reaction pathway for de novo synthesis of DNA building blocks and the enzyme is thus necessary for life. RNR is found in all but a few organisms. READ MORE

  6. 9. HLA class I maturation - in the presence and absence of tapasin

    Author : Linda Geironson Ulfsson; Biologiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Human leukocyte antigen class I (HLA-I) molecules are present on all nucleated cells and present the cell content to cytotoxic T lymphocytes in the form of peptides. Maturation of HLA-I occurs in the endoplasmic reticulum and results in stable peptide-HLA-I complexes, in the presence of proper quality control. READ MORE

  7. 10. MHC and Transgenic Mice. A study into polymorphism and function of class I and class II molecules

    Author : Mikael Vestberg; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MHC rat mouse transgenic autoimmunity collagen peptide; Clinical biology; Klinisk biologi;

    Abstract : Transplantation antigens encoded in the major histocompatibility complex (MHC) bind peptides and present them to T cells. We showed that mouse T cells expressing transgenic human CD8 can recognise human MHC class I. READ MORE