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Showing result 1 - 5 of 42 swedish dissertations matching the above criteria.

  2. 1. Evolutionary trajectories of Klebsiella pneumoniae : From experimental biofilm evolution to a hospital outbreak

    Author : Greta Zaborskytė; Linus Sandegren; Vaughn S. Cooper; Uppsala universitet; []
    Keywords : Klebsiella pneumoniae; evolution; experimental evolution; biofilms; infection; bacterial pathogens; Mikrobiologi; Microbiology;

    Abstract : Bacterial evolution is closely intertwined with our lives. As their hosts, we shape how bacteria evolve by imposing numerous selective pressures during the time bacteria spend in our bodies. As a result, they adapt in various ways to colonize us or infect us better. READ MORE

  4. 2. Multidrug-Resistant Escherichia coli and Klebsiella pneumoniae : Treatment, Selection and International Spread

    Author : Thomas Tängdén; Otto Cars; Anders Johansson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Escherichia coli; Klebsiella pneumoniae; extended-spectrum beta-lactamases; carbapenemases; metallo-beta-lactamases; synergy; antibiotic interventions;

    Abstract : The prevalence of Escherichia coli and Klebsiella pneumoniae producing extended-spectrum beta-lactamases (ESBLs) and carbapenemases is increasing worldwide. Therapeutic options for infections with these bacteria are limited not only by the production of ESBLs and carbapenemases, which confer resistance to cephalosporins and carbapenems, but also by frequent co-resistance to other antibiotics. READ MORE

  5. 3. Characterisation of Food Associated Bacteria by DNA based Methods, with Special Reference to Enterobacteriaceae

    Author : Crister Olsson; Livsmedelsteknik; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Food and drink technology; 16S rRNA; TTGE; ribotyping; Rahnella; Klebsiella; HPI; Enterobacteriaceae; food; Livsmedelsteknik;

    Abstract : The presence of genes in food, encoding some virulence factors, was studied by PCR, and species of Enterobacteriaceae, associated with food, were studied by the DNA-based methods of TTGE, ribotyping and sequencing. The flora of fresh and chill-stored pork were analysed by a culture-independent approach, using specific amplification of 16S rRNA genes followed by cloning and sequencing. READ MORE

  6. 4. Bacterial viruses targeting multi-resistant Klebsiella pneumoniae and Escherichia coli

    Author : Harald Eriksson; Anders Nilsson; Elisabeth Haggård-Ljungquist; Klas Flärdh; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Bacterial viruses; Bacteriophage; Phage; Phage therapy; multi-resistant bacteria; Klebsiella pneumoniae; molekylärgenetik; Molecular Genetics;

    Abstract : The global increase in antibiotic resistance levels in bacteria is a growing concern to our society and highlights the need for alternative strategies to combat bacterial infections. Bacterial viruses (phages) are the natural predators of bacteria and are as diverse as their hosts, but our understanding of them is limited. READ MORE

  7. 5. Carbapenemase-Producing Enterobacteriaceae in Wastewater-Associated Aquatic Environments

    Author : Faisal Ahmad Khan; Jana Jass; Bo Söderquist; Ann-Sofie Rehnstam-Holm; Örebro universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Antibiotic resistance evolution; ESBL; Klebsiella; Multidrug; VIM;

    Abstract : The emergence of carbapenem resistance due to the carbapenem-hydrolyzing enzymes (carbapenemases) in Enterobacteriaceae has led to limited therapeutic options. The increased resistance to these “last-resort” antibiotics is fueled by overuse and misuse of antibiotics in human medicine and agriculture. READ MORE