Search for dissertations about: "krebs cycle"

Found 5 swedish dissertations containing the words krebs cycle.

  1. 1. Mitochondrial Energy Metabolism : Kgd4 is a novel subunit of the α-ketoglutarate dehydrogenase complex

    University dissertation from Stockholm : Department of Biochemistry and Biophysics, Stockholm University

    Author : Manfred Heublein; Martin Ott; Flavia Fontanesi; [2014]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mitochondria; α-ketoglutarate dehydrogenase; Kgd4; Krebs cycle; biokemi; Biochemistry;

    Abstract : Mitochondria are essential organelles of eukaryotic cells and are responsible for their energy metabolism. The citric acid cycle, a chain of redox reactions in the mitochondrial matrix, is a central metabolic hub. READ MORE

  2. 2. Prostate Cancer Diagnosis experimental and Clinical Studies With HRMAS NMR Spectroscopy

    University dissertation from Umeå : Umeå universitet

    Author : Katarina Stenman; Katrine Åhlström-Riklund; Anders Bergh; Peter Lundberg; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; PCa; HRMAS NMR; MRSI; metabolomics; Gleason score; citrate; inositol; choline; Krebs cycle; PUFA; omega-6; omega-3; MEDICINE Physiology and pharmacology Radiological research Diagnostic radiology; MEDICIN Fysiologi och farmakologi Radiologisk forskning Diagnostisk radiologi; Radiology; radiologi;

    Abstract : A few abnormal cells found in a small piece of prostate tissue are most consequential for a man’s future. The prevalence of prostate cancer (PCa) is increasing globally. READ MORE

  3. 3. Metabolic intervention during blood cardioplegia. Clinical studies in coronary surgery and heart transplantation

    University dissertation from Göteborg

    Author : Ulf Kjellman; Göteborgs universitet.; Gothenburg University.; [2000]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiac surgery; heart transplantation; oxygen extraction; substrate metabolism; predictors of ischemic injuries; a - ketoglutarate; insulin;

    Abstract : Myocardial ischemia and injury (infarction) during open heart surgery and heart transplantation is a problem in spite of the fact that it is a safe procedure today. The myocardial substrate metabolism is well investigated before and after the cardioplegic period but little knowledge exists about the myocardial metabolic changes during cardioplegia. READ MORE

  4. 4. Protein phosphorylation cascades regulating islet beta-cell insulin exocytosis through glucose sensing and drug signaling : With special focus on serine/threonine protein phosphates and hypoglycemic sulfonylureas

    University dissertation from Stockholm : Karolinska Institutet, Karolinska Institutet, Stockholm Söder Hospital

    Author : Mikael Lehtihet; Karolinska Institutet.; Karolinska Institutet.; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Diabetes; Islet; Insulin; Exocytosis; Protein phosphatase; Protein kinase; CPT-1; Sulfonylurea; Glutamate; Polyphosphoinositide;

    Abstract : In human type 2 diabetes, loss of glucose-sensitive insulin secretion from the pancreatic -cell is an early pathogenetic event. Initially, this may be compensated for by stimulating insulin secretion by sulfonylurea drugs. READ MORE

  5. 5. The use of monogenic disease to study basal and disease associated mechanisms with focus on NGF dependent pain insensitivity and ISCU myopathy

    University dissertation from Umeå : Umea university, Department of Medical Biosciences

    Author : Elin Larsson; Monica Holmberg; Geoff Woods; [2012]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; monogenic; disease; NGF; receptor; pain insensitivity; ISCU; myopathy; splicing; molecular medicine medical sciences ; molekylär medicin medicinska vetenskaper ;

    Abstract : Monogenic diseases make excellent models for the study of gene functions and basal cellular mechanisms in humans. The aim of this thesis was to elucidate how genetic mutations affect the basal cellular mechanisms in the monogenic diseases Nerve growth factor (NGF) dependent pain insensitivity and Iron-Sulphur cluster assembly protein U (ISCU) myopathy. READ MORE