Search for dissertations about: "lDL, ATHEROSCLEROSIS"

Showing result 1 - 5 of 113 swedish dissertations containing the words lDL, ATHEROSCLEROSIS.

  2. 1. Development of a Passive Immunization Strategy Against Atherosclerosis

    Author : Alexandru Schiopu; Kardiovaskulär forskning - immunitet och ateroskleros; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; regression; plaque; peptide; oxidized LDL; immune system; carotid stenosis; cardiovascular diseases; apolipoprotein B-100; atherosclerosis; Kardiovaskulära systemet; Cardiovascular system; vascular injury; ultrasound; antibodies;

    Abstract : Atherosclerosis is a chronic inflammatory disease, characterized by the accumulation of lipids and fibrous tissue in the wall of medium and large-sized arteries. The characteristic culprit of the disease is the atheroma, or atherosclerotic plaque, a patchy thickening of the arterial wall which affects the lumen, inducing various degrees of stenosis. READ MORE

  4. 2. Effects of hypoxia on macrophage function in atherosclerosis

    Author : Ellen Knutsen Rydberg; Göteborgs universitet; []
    Keywords : atherosclerosis; hypoxia; macrophage; IL-8; oxidized LDL; oxysterols; 15-lipoxygenase-2;

    Abstract : Atherosclerosis is a complex disease, which affects large and medium sized arteries and is characterized by an arterial wall thickening. A constant supply of oxygen is needed to maintain cell functions in the atherosclerotic plaque. The oxygen distribution to the cells in the arterial wall depends on diffusion. READ MORE

  5. 3. Studies on the atherogenicity of apoB-containing lipoproteins in type 2 diabetes

    Author : Camilla Pettersson; Göteborgs universitet; []
    Keywords : Type 2 diabetes; metabolic syndrome; atherosclerosis; VLDL; LDL; secretory phospholipase A2 group V; inflammation; complement; apolipoprotein; lysozyme;

    Abstract : Type 2 diabetes (T2D) and the metabolic syndrome (MetS), two conditions that are rapidly increasing in prevalence, as well as the dyslipoproteinemia and subclinical inflammation characteristic for these conditions, are associated with an increased risk for developing and dying of cardiovascular disease (CVD). The aim of this thesis was to investigate possible atherogenic properties of very low-density lipoprotein (VLDL) and low-density lipoprotein (LDL) in T2D and MetS. READ MORE

  6. 4. Atherogenic lipoproteins and their interaction with proteoglycans

    Author : Christofer Flood; Göteborgs universitet; []
    Keywords : apolipoprotein B; atherosclerosis; LDL; proteoglycan; sPLA2; ; retention;

    Abstract : Atherosclerosis is a multi-factorial disease and its pathogenesis is still unclear. However, accumulating evidence during recent years has led to the concept that subendothelial retention of atherogenic lipoproteins is the initiating event in atherogenesis. READ MORE

  7. 5. Retention of atherogenic lipoproteins in atherogenesis

    Author : Maria Gustafsson; Göteborgs universitet; []
    Keywords : apolipoprotein B; atherosclerosis; LDL; LpL; proteoglycans; retention; sPLA2;

    Abstract : Atherosclerosis is the most common cause of death in the industrialized world. The diseaseis characterized by lipid accumulation and inflammation in the arterial wall, which may leadto obstruction of the blood flow. READ MORE