Search for dissertations about: "lactadherin"
Showing result 1 - 5 of 6 swedish dissertations containing the word lactadherin.
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1. Medin amyloid - a matter close to the heart : Studies on medin amyloid formation and involvement in aortic pathology
Abstract : Amyloidoses are a group of protein misfolding diseases characterized by deposits of insoluble fibrillar protein aggregates. Medin amyloid, which is the focus of this thesis, appears in the media of the thoracic aorta in nearly all individuals over 50 years. READ MORE
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2. Medin Amyloid in Human Arteries and its Association with Arterial Diseases
Abstract : Amyloid is a form of abnormal protein aggregation within the living body. Massive deposits can lead to organ failure. There is also increasing evidence that smaller pre-amyloid aggregates exert direct toxic effects to cells. READ MORE
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3. Microvesicles, skin microcirculation and clinical microangiopathy in type 1 diabetes
Abstract : Background: Type 1 diabetes is a proinflammatory and prothrombotic disease associated with a highly elevated risk of microvascular complications, including nephropathy, retinopathy, and neuropathy, as well as premature cardiovascular disease. Aim: this thesis sought to study plasma microvesicles (MVs) and skin microcirculation in relation to clinical microangiopathy in type 1 diabetes, to try to identify potential clinical biomarkers. READ MORE
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4. Studies of clinical and haemostatic features associated with antiphospholipid antibodies
Abstract : Background: Antiphospholipid antibodies (aPL) are associated with a heterogeneous range of clinical conditions with predisposition for thrombosis, pregnancy morbidity and other autoimmune disorders, most frequently systemic lupus erythematosus (SLE). Both the clinical manifestations themselves and their treatment may be harmful to the affected individuals and aPL testing is still controversial. READ MORE
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5. Apolipoprotein A-1 derived amyloid in the atherosclerotic intima of the human aorta
Abstract : Amyloid is insoluble fibrillar protein deposited in the extracellular space. The resulting heterogeneous group of disorders, amyloidosis, can be sporadic or hereditary, and the amyloid is systemically distributed or localized in single organs. READ MORE