Search for dissertations about: "lactone"
Showing result 1 - 5 of 35 swedish dissertations containing the word lactone.
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1. Some New Methods in Sialic Acid Chemistry
Abstract : Gangliosides (G) are sialic acid-containing cell surface glycosphingolipids capable of forming lactones, i.e. inner esters. Some gangliosides are tumor-associated antigens, and they may serve as immunogens in their lactone form, where the latter is comparatively more abundant on the surface of malignant cells. READ MORE
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2. Synthetic analogs of sialyl Lewis x
Abstract : The sialyl Lewis x (SLex) tetrasaccharide is the smallest recognizable ligand for selectins. The selectins constitute a vital part of the inflammatory cascade for recruitment of leukocytes to a site of tissue damage or microbial infection. READ MORE
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3. Studies of α-D-isosaccharinic Acid – Acid dissociation constant and structural conformations
Abstract : .... READ MORE
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4. On the Versatility of Microwave-Assisted Chemistry : Exemplified by Applications in Medicinal Chemistry, Heterocyclic Chemistry and Biochemistry
Abstract : Today, the demand for speed in drug discovery is constantly increasing, particularly in the iterative processes of hit validation and expansion and lead optimization. Irradiation with microwaves (MWs) has been applied in the area of organic synthesis to accelerate chemical reactions and to facilitate the generation of new chemical entities since 1986. READ MORE
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5. Evaluation of macrocyclic lactone resistance in gastrointestinal nematodes of first season grazing cattle
Abstract : Parasitic gastrointestinal nematodes (GIN) are common world-wide among grazing cattle, and cause welfare problems and associated economic losses due to reduced performance of their hosts. In Sweden, the most important GIN include Cooperia oncophora and the more pathogenic Ostertagia ostertagi, which are usually present as mixed infections in first season grazing cattle (FSG). READ MORE