Search for dissertations about: "lactones"
Showing result 1 - 5 of 36 swedish dissertations containing the word lactones.
-
1. Antigens derived from the mucin MUC1 : Solution and solid-phase synthesis of saccharides, peptides and glycopeptides
Abstract : Mucin is a term used to describe a large family of heavily glycosylated proteins which are present on the surfaces of secretory epithelial cells and are overexpressed by many carcinomas. Membrane-bound mucin MUC1 is of special interest. Its backbone consists of repeating units of twenty amino acids with five potential glycosylation sites. READ MORE
-
2. Biological Activities of Natural and Semi-Synthetic Pseudo-Guaianolides: Inhibition of Transcription Factors
Abstract : Damsin (1) is a natural sesquiterpene lactone (SL) isolated from Ambrosia arborescens Mill., a plant used in the Andes as antiinflammatory medicine. READ MORE
-
3. Exploring evolutionary and chemical space using chemoinformatic tools and traditional methods in pharmacognosy
Abstract : The number of new drugs coming to the market is declining while interest in lead discovery from natural resources is seeing a revival. Although methods for isolation and identification of natural products have advanced tremendously, methods for selection of potential leads have fallen behind. READ MORE
-
4. Phylogenies and Secondary Chemistry in Arnica (Asteraceae)
Abstract : The genus Arnica (Asteraceae) was investigated for phylogenetic relationships and sesquiterpene lactone (STL) content with the aims to trace the evolutionary history of the genus and to investigate possible congruencies between DNA sequence data, secondary chemistry, and biological activity. Complex evolutionary patterns in Arnica are evident from phylogenetic analyses of chloroplast regions (the rpl16 and rps16 introns and the psbA–trnH, ycf4–cemA, and trnT–L spacers), nuclear ribosomal regions (the internal and external transcribed spacers) and the nuclear low-copy DNA region coding for the second largest subunit of RNA polymerase II (RPB2) between exons 17 and 23. READ MORE
-
5. Thiol−ene Coupling of Renewable Monomers : at the forefront of bio-based polymeric materials
Abstract : Plant derived oils bear intrinsic double-bond functionality that can be utilized directly for the thiol–ene reaction. Although terminal unsaturations are far more reactive than internal ones, studies on the reversible addition of thiyl radicals to 1,2-disubstituted alkenes show that this is an important reaction. READ MORE