Search for dissertations about: "lamina propria lymphocyte"
Showing result 1 - 5 of 10 swedish dissertations containing the words lamina propria lymphocyte.
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1. Human intestinal T lymphocytes : a comparative analysis of phenotype and function in normal and inflamed mucosa
Abstract : The epithelial lining of the gut must allow immediate contact with beneficial components as nutrients and normal microflora. At the same time it runs the constant risk of attack from pathogenic microbes and noxious agents. READ MORE
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2. EFFECTOR T CELL HOMING TO THE SMALL INTESTINAL MUCOSA
Abstract : The intestinal mucosa, including the intestinal epithelium and underlying lamina propria (LP), contains a large number of effector/memory T cells that are thought to play a central role in the generation and maintenance of mucosal immune responses and in maintaining mucosal integrity. The work in this thesis investigates the mechanisms regulating effector T cell recruitment to the small intestinal mucosa focusing on the role of chemokine receptors in this process. READ MORE
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3. Adaptive immune response in the intestinal mucosa of microscopic colitis patients
Abstract : Microscopic colitis (MC) is a chronic diarrhoeal disease of unknown aetiology, comprising collagenous colitis (CC) and lymphocytic colitis (LC). The nature of the adaptive local immune responses in the mucosa of MC patients is however far from elucidated. READ MORE
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4. Specific and nonspecific immune mechanisms in human gut : a comparative study of normal and ulcerative colitis intestine
Abstract : The intestine, with its large mucosal surface area, digests and absorbs food nutrients and maintains a beneficial microbial flora in the colon. Local protective immune responses against intestinal pathogens ensure the survival of the individual. These immune reactions are both specific and non-specific in nature. READ MORE
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5. Extrathymic T cell receptor gene rearrangement in human alimentary tract
Abstract : T lymphocytes regulate the initiation, duration, and magnitude of adaptive immune responses and function as effector cells in cell mediated immunity. To become immunologically competent they must generate functional antigen receptors. This process takes place in the thymus and requires somatic recombination of T cell receptor (TCR) genes. READ MORE