Search for dissertations about: "langerhans cell histiocytosis"

Found 5 swedish dissertations containing the words langerhans cell histiocytosis.

  1. 1. Langerhans cell histiocytosis : detection, monitoring and pathophysiology

    Author : Ulrika Calming; Karolinska Institutet; Karolinska Institutet; []
    Keywords : LCH; detection; monitoring; cytokines;

    Abstract : Langerhans cell histiocytosis (LCH) is a rare disease that may occur at any age but mainly affects children. Clonally expanded Langerhans cells together with lymphocytes, eosinophils and macrophages form destructive granulomatous lesions in many various organs. The etiology and pathophysiology of the disease still remain elusive. READ MORE

  2. 2. Langerhans cell histiocytosis : a clinical and immunological study

    Author : Cecilia Bernstrand; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Langerhans cell histiocytosis LCH ; survival; follow-up; sequelae; lungs; CNS; monitoring; smoking; HLA;

    Abstract : Langerhans cell histiocytosis (LCH), previously known as histiocytosis X, eosinophilic granuloma, Hand-Schüller-Christian or Letterer-Siwe disease, is a rare disease with a reported incidence in childhood of 5.4 cases per million children per year. The disease can present at any age but young children are most often affected. READ MORE

  3. 3. Etiological and clinical studies of Langerhans cell histiocytosis (LCH)

    Author : Selma Olsson Åkefeldt; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Langerhans cell histiocytosis (LCH) is a rare disease of unknown origin. LCH may occur at any age but affects mainly children and the most severe forms of the disease are seen in the youngest children. In LCH, granulomatous lesions are formed in various organs. READ MORE

  4. 4. Human myeloid cells in cancer, inflammation, and infection

    Author : Eglė Kvedaraitė; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Myeloid cells are a part of innate immunity, playing a major role in orchestrating innate and adaptive immune responses. While work performed in experiment model systems has significantly increased our knowledge on fundamental myeloid cell functions, studies in well-designed clinical cohorts are important for understanding their functions in human health and disease, such as in cancer, infection and chronic inflammation. READ MORE

  5. 5. The role of monocytes in chronic inflammatory diseases

    Author : Sofia Björnfot Holmström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Monocytes and monocyte-derived cells are important players in the orchestration of inflammatory reactions in blood and peripheral tissues. However, little is known about the monocyte fate upon entry into human tissues, and current concepts are mainly based on animal models, with the addition of observational studies in humans that often do not allow determining causality. READ MORE