Search for dissertations about: "large dense core vesicles"

Showing result 1 - 5 of 9 swedish dissertations containing the words large dense core vesicles.

  2. 1. PROBING SECRETORY VESICLES AND LIPOSOME MODEL SYSTEMS USING NANOSCALE ELECTROCHEMISTRY AND MASS SPECTROMETRY

    Author : Jelena Lovric; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; neuroendocrine cells; NanoSIMS; liposomes; neurotransmitters; large dense core vesicles; Exocytosis; ToF-SIMS; vesicle electrochemical cytometry; electrochemistry; amperometry;

    Abstract : Cellular communication is based on the process of exocytosis, regulated release of chemical messengers into the extracellular space. These messengers, neurotransmitters, are packed into vesicles that during exocytosis fuse with the plasma membrane and release their content. READ MORE

  4. 2. Characterization of artificial and biological lipid vesicles using TIRF and SPR

    Author : Thomas Olsson; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; membrane permeability; chromaffin vesicle; fluorescence; total internal reflection TIRF microscopy; surface plasmon resonance SPR ; vesicle; osmotic shock; cell membrane; liposome; nanoparticle tracking analysis NTA ; large dense core vesicles LDCVs ;

    Abstract : Synthetic lipid vesicles serve as important mimics of cells and the natural membranes that they are enclosed by. As such they are frequently used as simplified models of the highly complex cell membrane to aid in-depth physicochemical and biological characterization of this essential biological structure. READ MORE

  5. 3. New Electrochemical Tools to Study Exocytosis

    Author : Joakim Wigström; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; amperometry; QCM-D; micro electrode array; large dense core vesicles; chromaffin cells; PC-12 cells; microelectrode; exocytosis; electrochemical cytometry; electrochemical imaging; acetylcholine; endocytosis; nanoparticles; enzyme biosensor; microfabrication;

    Abstract : The work described in this thesis has the focus on the development of new analytical tools to study processes related to cellular secretion (exocytosis) in cell models. Four novel techniques were developed, allowing new ways to study processes related to exocytosis, and gain previously unattainable knowledge. READ MORE

  6. 4. New Approaches for Chemical Analysis of Single Cells and Vesicles

    Author : Johan Dunevall; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Electrochemistry; Analytical chemistry; Chemistry; Exocytosis; Catecholamines;

    Abstract : Exocytosis is the major cell-to-cell communication process in the nervous system, involving the conversion of an electrical signal (e.g. action potential) to a chemical one. Signaling molecules like neurotransmitters, hormones and/or peptides are stored in vesicles inside the cell. READ MORE

  7. 5. Nature of Large Vesicle Exocytosis in Pancreatic β-cells: Release of ATP and GABA

    Author : Jovita Karanauskaite; Islet cell physiology; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ATP; LDCV; Insulin; exocytosis; Compound Exocytosis; Calcium;

    Abstract : Several high resolution electrophysiological techniques such as measurements of cell membrane capacitance and amperometry are used to detect exocytotic events. A novel method was developed in this study based on the expression of P2X2 receptor channel in secreting cells. READ MORE