Search for dissertations about: "large pedigree"
Showing result 1 - 5 of 23 swedish dissertations containing the words large pedigree.
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1. Genetic studies of schizophrenia
Abstract : The prevalence of schizophrenia is about 1% throughout the world. The disease is characterized by symptoms such as hallucinations, delusions and bizarre behavior. A genetic contribution to the disease was previously shown through epidemiological studies. The mitochondrial DNA was sequenced in four schizophrenic patients. READ MORE
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2. Detecting Deletions by Analysis of Genetic Markers in Pedigrees
Abstract : A deletion is defined as a missing piece of a chromosome, ranging in size from as small as a single base pair to as much as an entire arm of a chromosome. Deletions can cause diseases, but may also have a neutral effect in the genome. READ MORE
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3. Finding Genes for Schizophrenia
Abstract : Schizophrenia is one of our most common psychiatric diseases. It severely affects all aspects of psychological functions and results in loss of contact with reality. No cure exists and the treatments available today produce only partial relief for disease symptoms. READ MORE
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4. Dynamics of inbreeding and genetic rescue in a small population
Abstract : Isolation at small population size can reduce individual fitness and impede population growth caused by inbreeding and genetic drift (i.e. inbreeding depression). Inbreeding depression can however be circumvented by gene flow from unrelated individuals through masking of recessive deleterious alleles and contribute to population persistence (i. READ MORE
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5. Gene Mapping in Ficedula Flycatchers
Abstract : In order to get full understanding of how evolution proceeds in natural settings it is necessary to reveal the genetic basis of the phenotypic traits that play a role for individual fitness in different environments. There are a few possible approaches, most of which stem from traditional mapping efforts in domestic animals and other model species. READ MORE