Search for dissertations about: "latanoprost acid"

Found 2 swedish dissertations containing the words latanoprost acid.

  1. 1. A study on the vascular effects of prostaglandin F2α[ and latanaprost in the eye with special reference to the surface hyperaemia after topical administration

    Author : Maria Astin; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; Prostaglandin F2a; Prostaglandin F2a-isopropyl ester; latanoprost; latanoprost acid; ocularhyperaemia; blood flow; sensory nerves; veins; arteries; nitric oxide; substance P; CGRP; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci; Pharmacognosy; farmakognosi;

    Abstract : The ocular hypotensive effect of topically applied prostaglandins is usually accompanied byconjunctival hyperaemia and irritation. The purpose of the present study was to investigate thepharmacological mechanism of the ocular surface hyperaemia induced by topically appliedprostaglandins, particularly prostaglandin F2α (PGF2α) and its synthetic analogue latanoprost, aselective FP prostanoid receptor agonist. READ MORE

  2. 2. The prostanoid FP receptor and uveoscleral outflow : A study of FP receptor expression and functions in the eye

    Author : Anette Ocklind; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Prostanoid FP receptor; tissue distribution; ciliary muscle; iris sphincter muscle; extracellularmatrix; actin; prostaglandin F2a; latanoprost; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Abstract : Prostaglandin F2α is a prostanoid FP receptor agonist which acts as an intraocular pressure-lowering agent by increasing the uveoscleral outflow of aqueous humour through the ciliary muscle. The aim of this, thesis was to investigate possible mechanisms of the increased uveoscleral outflow induced by prostaglandin F2α and its analogue latanoprost acid. READ MORE