Search for dissertations about: "late genes"

Showing result 1 - 5 of 231 swedish dissertations containing the words late genes.

  2. 1. Candidate Genes for Late Diabetic Complications

    Author : Eero Lindholm; diabetes och endokrinologi Genomik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TNF; sekretion; LTA; Endocrinology; nephropathy; diabetes mellitus; retinopathy; neuropathy; genetic; UCP; diabetologi; AGER; MHc2TA; HLA-DQB1; Endokrinologi; secreting systems; diabetology;

    Abstract : Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. The new WHO criteria for classification of diabetes takes into account also clinical stages dividing the diabetic patients into noninsulin requiring (NIR), insulin requiring for control (IRC) and insulin requiring for survival (IRS) subgroups. READ MORE

  4. 2. Control of human papillomavirus type 1 late mRNA stability and translation by an AU-rich RNA element

    Author : Marcus Sokolowski; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; HPV-1; HPV-16; late genes; 3´ UTR; L1; L2; c-fos; AU rich element; HuR; hnRNP C1 C2; mRNA stability; translation; Biokemi; Biochemistry; Biokemi; Medical Virology; medicinsk virologi;

    Abstract : Human Papillomaviruses (HPVs) infect the epithelial tissues in humans and infection with certain high-risk types is associated with cancer. The expressionof the HPV late capsid genes is dependent on cell differentiation. This may be one reason for the lack of HPV replication in vitro. READ MORE

  5. 3. On the influence of dopamine-related genetic variation on dopamine-related disorders

    Author : Olle Bergman; Göteborgs universitet; []
    Keywords : dopamine; neurodevelopment; amygdala; schizophrenia; Parkinson s disease; social anxiety disorder; ADHD; PITX3; LMX1A; LMX1B; BDNF; DAT; SNP; genes; genetics; BDNF;

    Abstract : Rationale: Dopamine synthesizing neurons are involved in a wide variety of functions. The most prominent dopamine pathways originate in the midbrain. The development, function and survival of these dopaminergic neurons are under the influence of numerous transcription and neurotrophic factors. READ MORE

  6. 4. Investigating the impacts of Late Pleistocene climate change on Arctic mammals using palaeogenomics

    Author : Edana Lord; Love Dalén; Mirte Bosse; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; palaeogenomics; Arctic; Late Pleistocene; past climate; collared lemming; woolly rhinoceros; Norwegian lemming; muskox; demography; population structure; speciation; adaptation; genome erosion; Systematic Zoology; zoologisk systematik och evolutionsforskning;

    Abstract : The climatic fluctuations of the Late Pleistocene likely had a large impact on the evolutionary history of Arctic species. Palaeogenomics is a useful tool to shed light on how past populations responded to these climatic shifts and the associated ice sheet dynamics and sea level change. READ MORE

  7. 5. Association studies on susceptibility genes in Alzheimer disease

    Author : Behnosh Fakhri Björk; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Our results support the involvement of genetic variants in IDE; TFAM and COL25A1 in AD cases from Sweden; whereas; it does not for PITRM1.;

    Abstract : Alzheimer disease (AD) is the most common form of dementia in the elderly. Due to the complexity of AD, it has been difficult to find genetic risk factors predisposing to disease. To date, three genes (APP, PSEN1 and PSEN2) with disease causing genetic variants have been reported for the rare early onset monogenic forms of AD. READ MORE