Search for dissertations about: "latent autoimmune diabetes in adults LADA"

Showing result 1 - 5 of 12 swedish dissertations containing the words latent autoimmune diabetes in adults LADA.

  1. 1. Clinical, Genetic and Metabolic Characterisation of LADA (Latent Autoimmune Diabetes in Adults)

    University dissertation from ÅsaLinda Lethagen Wallenberg Laboratory ing 46, Malmö University Hospital, 20502 Malmö, Sweden

    Author : ÅsaLinda Lethagen; Lund University.; Lunds universitet.; [2002]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; metabolic syndrome; insulin sensitivity; insulin secretion; GADabs; glutamic acid decarboxylase autoantibodies; Type 2 diabetes; LADA; Type 1 diabetes; IDDM1; IDDM2; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Abstract : Latent autoimmune diabetes in adults (LADA) comprises about 10% of patients initially diagnosed with type 2 diabetes but who are positive for pancreatic islet antibodies, especially to glutamic acid decarboxylase (GADabs). The present studies focused on clinical, genetic and metabolic characterisation of patients with LADA. READ MORE

  2. 2. Genetics of diabetic subtypes

    University dissertation from Department of Clinical Sciences, Lund University

    Author : Camilla Cervin; Lund University.; Lunds universitet.; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endocrinology; secreting systems; diabetology; Endokrinologi; Mutation; Association; Genetics; LADA; Diabetes; MODY; sekretion; diabetologi;

    Abstract : There are two major types of diabetes mellitus, Type 1 Diabetes (T1D) and Type 2 Diabetes (T2D), however a number of subtypes have been defined and classified. Maternally Inherited Diabetes and Deafness (MIDD) and Maturity Onset Diabetes of the Young (MODY) are monogenic forms, whereas Latent Autoimmune Diabetes in Adults (LADA) is thought to be a polygenic subtype similar to T1D. READ MORE

  3. 3. Genetic interaction between Type 1 and Type 2 diabetes

    University dissertation from Haiyan Li, Wallenberg Laboratory ing 46, Malmö University Hospital, 20502 Malmö, Sweden

    Author : Haiyan Li; Lund University.; Lunds universitet.; [2002]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endocrinology; IDDM2.; Insulin gene VNTR; HLA; IDDM1; mixed type 1 2; Mixed type 1 type 2 diabetes families; LADA; GADabs; Autoantibodies against GAD65; Type 1 diabetes; Type 2 diabetes; diabetology; secreting systems; sekretion; diabetologi; Endokrinologi;

    Abstract : There are two major types of diabetes, type 1 and type 2 diabetes. Similarly characterized by hyperglycaemia and long term micro- and macrovascular complications, type 1 and type 2 diabetes have different underlying pathophysiologic processes. In Scandinavia, type 1 diabetes is common; type 2 diabetes accounts for 85% of all cases with diabetes. READ MORE

  4. 4. Autoimmune markers in autoimmune diabetes

    University dissertation from Stockholm : Karolinska Institutet, Department of Molecular Medicine

    Author : Manu Gupta; Karolinska Institutet.; Karolinska Institutet.; [2004]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HLA; MICA; type 1 diabetes; LADA; Coxsackie virus B; autoantibodies; newborn screening;

    Abstract : Type 1 diabetes mellitus (T1DM) is an autoimmune disease, characterized by autoimmune mediated loss of insulin secreting Beta-cells. The disease is associated with certain HLA class 11 haplotypes. HLA DR3-DQ2 and DR4-DQ8 are positively while DQ6 (DQA1*0102-DQB1*0602) is negatively associated with the disease in Caucasians. READ MORE

  5. 5. Exploring the Grey Zone between Type 1 and Type 2 Diabetes

    University dissertation from Department of Clinical Sciences, Lund University

    Author : Ekaterine Bakhtadze; Lund University.; Lunds universitet.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : T1D is most common in children and young adults and is characterized by autoimmune destruction of insulin producing pancreatic beta cells, presence of certain risk genotypes such as HLA-DQB1, INS VNTR, PTPN22 and need of insulin for survival. In adults the same situation is often referred to as Latent Autoimmune Diabetes in Adults (LADA), with age at onset after 35 years and non-insulin requiring at least for 6 month after diagnosis. READ MORE