Search for dissertations about: "leaving strategy"

Showing result 6 - 10 of 26 swedish dissertations containing the words leaving strategy.

  2. 6. Development of 18F- and 68Ga-Labelled Tracers : Design Perspectives and the Search for Faster Synthesis

    Author : Elisabeth Blom; Bengt Långström; Oleksiy Itsenko; Irina Velikyan; Farhad Karimi; Frank Rösch; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; PET; nucleophilic 18F-fluorination; perfluoro; F-SPE; molecular design; 68Ga; chelators; DOTA; NOTA; microwave; halogen exchange; harmine; biotin; RGD; VEGF; CRP; Chemistry; Kemi; Organisk kemi; Organic Chemistry;

    Abstract : This thesis deals with the design of 18F- and 68Ga-labelled positron emission tomography (PET) tracers and the development of technologies that enable faster and simpler preparation with high specific radioactivity. Techniques like microwave heating and reducing the concentrations of the precursor were investigated with this perspective. READ MORE

  4. 7. Investigating novel roles of topoisomerase regulatory interactions in transcription

    Author : Vladislav Kuzin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Drugs targeting DNA Topoisomerases (TOPs, TOP1 and TOP2) are mainstays of anti-cancer therapy. While they have proven effective, the toxicity of current TOP drugs caused by DNA damage-induced apoptosis of non-cancer cells, limits their use in the clinic. READ MORE

  5. 8. Peatland hydrology in boreal Sweden: Modelling, long-term data analysis, and experimental rewetting

    Author : Shirin Karimi; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Peatlands are the dominant type of wetland in boreal ecosystems and they are thought to play a major role in moderating hydrological extremes such as floods and droughts. Despite the valuable ecosystem services that they provide, a large proportion of peatlands around the globe has been degraded by human activity. READ MORE

  6. 9. Attract, reward and disrupt: combining habitat manipulation and semiochemicals to enhance pest control in apple orchards

    Author : Joakim Pålsson; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Abstract : Agricultural intensification entails negative effects on natural enemy populations and the pest regulation services they provide. Habitat manipulation holds potential to control pests with less negative effects on the environment than conventional methods. READ MORE

  7. 10. Asymmetric Synthesis using Redox-Active Diazocompounds as Chiral Carbon Atom Precursors

    Author : Matteo Costantini; Abraham Mendoza; Armido Studer; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; redox-active carbenes; mechanistic investigation; cyclopropanes; asymmetric catalysis; photochemistry; organisk kemi; Organic Chemistry;

    Abstract : This thesis summarizes the development of general and efficient methods to synthesize enantiomerically enriched cyclopropane compounds. The works reported herein exploit the opportunity presented by redox-active esters to explore the orthogonality between asymmetric carbene-transfer and geminal radical generation. READ MORE