Search for dissertations about: "left ventricular fibrosis"
Showing result 1 - 5 of 12 swedish dissertations containing the words left ventricular fibrosis.
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1. Mechanical and histological disturbances in advanced heart failure and cardiac transplantation
Abstract : The general purpose of this thesis is to establish capability and accuracy of speckle tracking echocardiography (STE) in assessing left atrial (LA), left ventricular (LV) and right ventricular (RV) function and their correlation with myocardial fibrosis, filling pressure and clinical outcomes in advanced heart failure (HF) patients before and after heart transplantation (HT).I demonstrated that HT recipients had impaired LV twist dynamics in the form of reduced rotation twist angle and untwist rate but time to peak twist was not different from the age matched controls and other cardiac surgical patients. READ MORE
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2. Insights into left atrial response to pressure and volume overload
Abstract : The general purpose of this thesis is to establish the ability of Speckle Tracking Echocardiography (STE) in assessing left atrial (LA) response to pressure and volume overload respectively in aortic stenosis (AS) and mitral regurgitation (MR), and to evaluate its accuracy in predicting LA and right ventricular (RV) fibrosis in patients with end-stage heart failure (HF) undergoing heart transplantation (HTx).I demonstrated that assessment of left ventricular (LV) long axis systolic velocity and amplitude of excursion is more sensitive than simple determination of ejection fraction (EF) for revealing the beneficial impact of MR surgery on overall LV systolic performance. READ MORE
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3. Diastolic heart function in hypertension-induced left ventricular hypertrophy
Abstract : Hypertensive left ventricular (LV) hypertrophy is an independent strong risk factor for cardiovascular morbidity and mortality. An abnormal diastolic relaxation in the absence of systolic impairment is often seen in patients with hypertension, whether LV hypertrophy is present or not. READ MORE
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4. Biomarkers of fibrosis in heart failure and relations to left ventricular size, function and outcome
Abstract : Background: Heart failure (HF) is a syndrome with impaired quality of life and higher mortality than most forms of cancer. The excessive accumulation of collagen in the myocardial extracellular matrix is called myocardial fibrosis, which is a reaction to myocardial stress, myocardial injury and a part of the remodeling process that alters the shape, size, and function of the heart. READ MORE
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5. Assessment of myocardial viability using magnetic resonance imaging
Abstract : Myocardial infarction (MI) following an acute coronary occlusion is a leading cause of morbidity and mortality. During revascularization, microemboli may complicate treatment and affect cardiac function. The long-term effects of microembolization are not fully elucidated. READ MORE