Search for dissertations about: "lenograstim"

Found 2 swedish dissertations containing the word lenograstim.

  2. 1. Kostmann syndrome : a clinical and pathophysiological study

    Author : Göran Carlsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Kostmann syndrome; severe congenital neutropenia; autosomal recessive; periodontitis; antibacterial peptides; LL-3 7; apoptosis; Bcl-2; granulocyte colony-stimulating factor; glycosylation; lenograstim; filgrastim.;

    Abstract : Kostmann syndrome or severe congenital neutropenia (SCN) is a rare disease, usually diagnosed during the first months of life, characterized by extremely low levels of neutrophils in the peripheral blood, a maturational arrest of the myelopoiesis in the bone marrow and severe bacterial infections. The purpose of this project was to improve the understanding of the clinical course and the pathophysiology of autosomal recessive SCN. READ MORE

  4. 2. Clinical and Experimental Studies in Chronic Myeloid Leukemia : Studies of Treatment Outcome, In Vitro Cellular Drug Resistance and Gene Expression

    Author : Ulla Olsson-Strömberg; Bengt Simonsson; Elin Lindhagen; Gisela Barbany; Johan Richter; Uppsala universitet; []
    Keywords : Medicine; chronic myeloid leukemia; adult; stem cell transplantation; mobilization of Ph-negative stem cells; in vitro assay; imatinib; gene expression; Medicin;

    Abstract : The aims of the studies described in the thesis were to investigate different treatment strategies in chronic myeloid leukemia (CML) patients. Furthermore, activity of imatinib was investigated by in vitro cytotoxicity assay, and the gene expression pattern in interferon treated patients. READ MORE