Search for dissertations about: "leptin, insulin resistance thesis"
Showing result 1 - 5 of 47 swedish dissertations containing the words leptin, insulin resistance thesis.
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1. Leptin : a risk marker for cardiovascular disease
Abstract : A major cause of morbidity and early death in the Western societies is cardiovascular disease (CVD) secondary to atherosclerotic disease. Metabolic aberrations have been linked to CVD. READ MORE
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2. Polycystic ovary syndrome : A study on factors of potential impact on body fat and carbohydrate metabolism
Abstract : The aim of the present thesis was to investigate some factors underlying the metabolic, anthropometric, and endocrine abnormalities of women with the polycystic ovary syndrome (PCOS).An iv insulin tolerance test (0.15 IU bolus) showed substantially preserved glucose counterregulation in women with PCOS (n=18). READ MORE
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3. Insulin-like Growth Factor-I (IGF-I) and Interleukin-6 (IL-6) regulate body fat
Abstract : The aim of this thesis was to investigate the role of insulin-like growth factor-I (IGF-I) and interleukin-6 (IL-6) in the regulation of metabolism and body fat mass. Circulating IGF-I is mainly liver derived, while a large part of circulating IL-6 is produced by adipose tissue. READ MORE
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4. Interplay between hormones, nutrients and adipose depots in the regulation of insulin sensitivity : an experimental study in rat and human adipocytes
Abstract : Obesity and specifically central obesity is related to insulin resistance, type 2 diabetes and other components of the so-called metabolic syndrome. The aim of this study was to elucidate the interplay between hormones, nutrients and adipose depots in normal and insulin-resistant fat cell metabolism. READ MORE
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5. Insulin resistance and cardiovascular function - Observational, translational and interventional studies
Abstract : Background: Microvascular disease is now recognized as an important driver for cardiovascular mortality and morbidity. Diabetic patients are known to suffer from this condition, leading to e.g. coronary ischemia as well as kidney dysfunction. READ MORE