Search for dissertations about: "leptin"

Showing result 1 - 5 of 127 swedish dissertations containing the word leptin.

  1. 1. Leptin a risk marker for cardiovascular disease

    Author : Stefan Söderberg; Ulf de Faire; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; leptin; testosterone; dysfibrinolysis; hyperinsulinemia; insulin resistance syndrome; menopause; cardiovascular disease; MONICA; epidemiology;

    Abstract : A major cause of morbidity and early death in the Western societies is cardiovascular disease (CVD) secondary to atherosclerotic disease. Metabolic aberrations have been linked to CVD. READ MORE

  2. 2. Leptin endocrinology and energy homeostasis in salmonids

    University dissertation from University of Gothenburg

    Author : Marcus Johansson; Göteborgs universitet.; Gothenburg University.; [2016]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Leptin; Leptin binding-protein; Energy homeostasis; Oncorhynchus mykiss; Salvelinus alpinus; Adiposity; Food intake; Fasting; Refeeding; Catabolism; Anorexia;

    Abstract : In salmonids, the physiological role of leptin is not completely elucidated. Nonetheless, the anorexigenic effect of leptin indicates a role in their energy homeostasis. This thesis focuses on advancing the understanding of the involvement of the leptin system in the regulation of energy homeo-stasis and food intake in teleost fish. READ MORE

  3. 3. Regulation of Leptin by Sexual Maturation and Energy Status in Male Atlantic Salmon (Salmo salar L.) Parr

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Susanne Trombley; Monika Schmitz; Sylvie Dufour; [2014]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Leptin; leptin receptor; Atlantic salmon; Salmo salar; sexual maturation; puberty; energy balance; hepatocytes; sex steriods; Biology with specialization in Comparative Physiology; Biologi med inriktning mot jämförande fysiologi;

    Abstract : Leptin is a peripheral adiposity signal and a key hormone in energy balance regulation in mammals, acting as a link between nutritional status and the endocrine reproductive axis. If this is also the role of leptin in fish is not fully understood. READ MORE

  4. 4. The role of leptin in endothelial dysfunction and cardiovascular disease

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Manuel Cruz Gonzalez Garcia; Stefan Söderberg; Jan Engvall; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; leptin; obesity; endothelial dysfunction; cardiovascular disease; Cardiology; kardiologi;

    Abstract : Objective:  Obesity has become the leading cause of mortality worldwide; however, the fundamental pathophysiology underlying this association remains unclear. The discovery of adipokines, i.e., cytokines produced by adipose cells (adipocytes), revealed that adipose tissue is a highly endocrine organ, thus opening new lines of investigation. READ MORE

  5. 5. Genes implicated in the development of obesity and obesity-related disease

    University dissertation from Göteborg

    Author : Kajsa Lindell; Göteborgs universitet.; Gothenburg University.; [2001]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; obesity; adipose tissue; hypothalamus; leptin; leptin receptor; 5 untranslated region; hypertension; angiotensinogen; DNA microarray;

    Abstract : Obesity is a major health problem because of its dramatic increase in prevalence and the association of obesity with type 2 diabetes, coronary heart disease, hypertension and stroke. Although mutations in certain genes have been shown to cause obesity, the molecular mechanisms underlying obesity and obesity-related disease are still largely unknown. READ MORE