Search for dissertations about: "let-7"

Found 5 swedish dissertations containing the word let-7.

  2. 1. The Regulatory Role of microRNAs in the Mouse and Human Brain

    Author : Rebecca Petri; Molekylär neurogenetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; microRNA; Argonaute; AGO-RIP; let-7; miR-125; adult neurogenesis; olfactory bulb; autophagy; transposable elements; LINE-2; Huntington’s disease;

    Abstract : microRNAs (miRNAs) are 20-24 nucleotides small, single-stranded, non-coding RNAs. They associate with Argonaute (AGO) proteins and exert their function by inhibition or degradation of messenger RNAs. READ MORE

  4. 2. Novel mechanisms in depression: focus on telomere biology and epigenetic regulation

    Author : Yabin Wei; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Telomere length;

    Abstract : Depression is a complex disorder with an average lifetime prevalence from 11.1% to 14.6%. It causes serious disability and is a significant public health problem worldwide. READ MORE

  5. 3. Signaling pathways in Drosophila immunity

    Author : Shiva Seyedoleslami Esfahani; Ylva Engström; Steven Wasserman; Stockholms universitet; []
    Keywords : Drosophila immunity; signaling pathways; Cactus; NFκB; Molecular Biology; molekylärbiologi;

    Abstract : Drosophila relies on innate immunity to protect itself from its hostile environment throughout its life cycle. Despite the remarkable progress in understanding many aspects of Drosophila immunity, there are still big gaps in our knowledge. READ MORE

  6. 4. CYTOGENETIC AND MOLECULAR GENETIC CHARACTERIZATION OF LIPOMAS

    Author : Hammurabi Bartuma; Avdelningen för klinisk genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; soft tissue tumors; adipocytic tumors; conventional lipomas; spindle cell lipoma; HMGA2; cytogenetic; molecular genetic; SNP array; GGE;

    Abstract : The focus of this thesis was to study cytogenetic and molecular genetic aberrations in lipomas. For this purpose, chromosome banding analysis, fluorescence in situ hybridization (FISH), as well as high resolution single nucleotide polymorphism (SNP)–arrays were used to identify recurrent chromosomal aberrations in lipomas. READ MORE

  7. 5. MicroRNAs and their processing factors in Caenorhabditis elegans and human cancers

    Author : Roger Kae-Jia Chang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : MicroRNAs (miRNAs) are small noncoding RNAs approximately 20-22 nucleotides (nt) long. These small RNAs (sRNAs) was initially discovered in Caenorhabditis elegans (C. elegans), but is conserved in over 50 animal species. READ MORE