Advanced search

Showing result 1 - 5 of 30 swedish dissertations matching the above criteria.

2. 1. Functions of small leucine-rich repeat proteoglycans in connective tissues

   Author : Sebastian Kalamajski; Åke Oldbergs forskargrupp; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Abstract : Biological properties of connective tissues rely heavily on collagen and its use in formation of extracellular networks (matrices) in which cells can live and move. To regulate the process of collagen matrix assembly, the cells secrete small leucine-rich repeat proteoglycans (SLRPs) that bind to collagen and influence its fibril formation. READ MORE

4. 2. Studies on chondroadherin-an extracellular matrix leucine-rich repeat protein

   Author : Christina Wenglén; Reumatologi och molekylär skelettbiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk biologi; Clinical biology; COMP; SLRP; ECM; collagen; cartilage; chondroadherin;

   Abstract : This thesis describes chondroadherin, one of the leucine-rich repeat proteins in the extracellular matrix (ECM) of cartilage. Chondroadherin defines a subgroup of its own by not having an N-terminal extension, having a different cysteine pattern and by being devoid of carbohydrate substitutions. READ MORE

5. 3. The role of leucine-rich repeat glycoproteins/proteoglycans in the assembly of collagen matrices

   Author : Liz Svensson; Institutionen för experimentell medicinsk vetenskap; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reumatologi; muskelsystem; Skelett; decorin; Collagen; fibromodulin; extracellular matrix; lumican; collagen fibrillogenesis; Skeleton; rheumatology locomotion; muscle system; Biochemistry; Biokemi; Metabolism;

   Abstract : The properties of different connective tissues depend on the synthesis and assembly of macromolecular structures composed of collagen and other extracellular matrix components. Mechanisms modulating these events play important roles in the formation of a functional tissue. READ MORE

6. 4. The Identification and Characterisation of LRIG Gene Family and Its Expression in Astrocytic Tumours

   Author : Dongsheng Guo; Tomas Ekström; Umeå universitet; []
   Keywords : astrocytoma; brain; EGFR; LRIG; leucine-rich repeat; real-time RT-PCR; onkologi; Oncology;

   Abstract : Gliomas are the most common primary brain tumours, and their capacity to invade surrounding normal brain prevents complete removal of the tumour. Malignant glioma has still a poor prognosis. However, with the rapid development of molecular biology our understanding about glioma has increased dramatically. READ MORE

7. 5. Molecular studies on streptococcal surface proteins

   Author : Johan Waldemarsson; Avdelningen för medicinsk mikrobiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nonimmunodominance; vaccine; camouflaging; Streptococcus agalactiae; leucine-rich repeat; Streptococcus pyogenes; alpha; fibrinogen; M protein; surface proteins; Rib;

   Abstract : Streptococcus agalactiae and Streptococcus pyogenes are two related human pathogens causing different diseases. This thesis focuses on a number of surface proteins expressed by S. agalactiae and S. pyogenes and, more specifically, the molecular and biological characterization of these proteins. READ MORE