Search for dissertations about: "leukemia RISK FACTORS thesis"

Showing result 1 - 5 of 58 swedish dissertations containing the words leukemia RISK FACTORS thesis.

2. 1. Perinatal Risk Factors for Childhood Leukemia

   Author : Estelle Naumburg; Eleni Petridou; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics and gynaecology; Childhood leukemia; infant leukemia; leukemia epidemiology; supplementary oxygen; perinatal risk factors; perinatal infection; prenatal ultrasound; prenatal x-ray; Obstetrik och kvinnosjukdomar; Obstetrics and women s diseases; Obstetrik och kvinnosjukdomar; pediatrik; Pediatrics;

   Abstract : The aim of the studies described in this thesis was to assess the association between certain perinatal factors and the risk of childhood lymphatic and myeloid leukemia and infant leukemia. The five studies presented were all conducted in Sweden as population-based case-control studies. READ MORE

4. 2. IKAROS and LEUKEMIA

   Author : Linda Olsson; Avdelningen för klinisk genetik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pediatric acute lymphoblastic leukemia; relapse; risk-stratifying factors; IKZF1; cooperative changes;

   Abstract : Acute lymphoblastic leukemia (ALL) is characterized by an accumulation of immature lymphoid cells in the bone marrow and is the most common cancer type in children. It is an immunophenotypically, morphologically, clinically, and genetically heterogeneous disorder that comprises several distinct subtypes. READ MORE

5. 3. Prognostic factors, treatment and outcome in adult acute lymphoblastic leukemia : Population-based studies in Sweden

   Author : Piotr Kozlowski; Helene Hallböök; Maria Åström; Anita W. Rijneveld; Örebro universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute Lymphoblastic Leukemia; adult; chemotherapy; prognosis; population-based; Onkologi; Oncology;

   Abstract : Acute lymphoblastic leukemia (ALL) has poor prognosis in older/elderly adults and in high-risk/relapsed disease. Recommended treatment of ALL was evaluated (study I-IV). Data was obtained from the Swedish Acute Leukemia registries and from patient records.I. READ MORE

6. 4. Leukemia Initiation in MLL-ENL Mediated Leukemogenesis

   Author : Amol Ugale; Avdelningen för molekylär hematologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematopoiesis; Luekemia; Cell of origin; Leukemia Initiation;

   Abstract : In the blood system, knowledge on the regulation of hematopoietic stem cells (HSCs) and their immature progeny has provided roadmaps of differentiation. Such information can also have a value to understand the etiology of hematological cancers, since clinical heterogeneity and prognostic therapeutic outcomes have been proposed to associate with the specific developmental stage from which the transformed cells originate. READ MORE

7. 5. Molecular epidemiology approach : nested case-control studies in glioma and lymphoid malignancies

   Author : Florentin Späth; Beatrice S. Melin; Carl Wibom; Ann Sofie Johansson; Ingvar Bergdahl; Ola Landgren; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioma; B cell lymphoma; multiple myeloma; risk; repeated samples; prospective longitudinal study; nested case-control study; circulating sEGFR and sERBB2; circulating immune markers and growth factors; marker disease association; disease progression; NSHDS; Janus; linear mixed modeling; epidemiologi; Epidemiology; Oncology; onkologi;

   Abstract : BACKGROUND: Nested case-control studies aim to link molecular markers with a certain outcome. Repeated prediagnostic samples may improve the evaluation of marker-disease associations. However, data regarding the benefit of repeated samples in such studies are sparse. READ MORE