Search for dissertations about: "leukemia thesis"

Showing result 1 - 5 of 369 swedish dissertations containing the words leukemia thesis.

  1. 1. Perinatal Risk Factors for Childhood Leukemia

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Estelle Naumburg; Uppsala universitet.; [2002]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics and gynaecology; Childhood leukemia; infant leukemia; leukemia epidemiology; supplementary oxygen; perinatal risk factors; perinatal infection; prenatal ultrasound; prenatal x-ray; Obstetrik och kvinnosjukdomar; MEDICINE Surgery Obstetrics and women s diseases; MEDICIN Kirurgi Obstetrik och kvinnosjukdomar; pediatrik; Pediatrics;

    Abstract : The aim of the studies described in this thesis was to assess the association between certain perinatal factors and the risk of childhood lymphatic and myeloid leukemia and infant leukemia. The five studies presented were all conducted in Sweden as population-based case-control studies. READ MORE

  2. 2. IKAROS and LEUKEMIA

    University dissertation from Division of Clinical Genetics, Lund University

    Author : Linda Olsson; Lunds universitet.; Lund University.; [2014]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pediatric acute lymphoblastic leukemia; relapse; risk-stratifying factors; IKZF1; cooperative changes;

    Abstract : Popular Abstract in Swedish Den vanligaste barncancerformen är akut leukemi, en form av blodcancer som uppstår i immunförsvarets celler och som drabbar cirka 75 barn i Sverige varje år. Även om de flesta av barnen idag botas får en av fem återfall och då minskar överlevnaden drastiskt trots intensiv behandling. READ MORE

  3. 3. Population-based studies on acute leukemias - lessons from the Swedish Adult Acute Leukemia Registry

    University dissertation from Division of Clinical Genetics, Lund University

    Author : Lovisa Vennström; Göteborgs universitet.; Gothenburg University.; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute leukemia; population-based; incidence; survival; acute myeloid leukemia; acute lymphoblastic leukemia; acute promyelocytic leukemia; early death;

    Abstract : Acute leukemia (AL) is a rare, potentially curable, aggressive neoplasm of hematopoietic origin. AL is a heterogeneous disease and is further subdivided according to clinical and biological features. READ MORE

  4. 4. Hairy cell leukemia : with special reference to in vitro effects of alpha-interferon treatment

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Inaam Bashir Hassan; Uppsala universitet.; [1991]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE; MEDICIN;

    Abstract : .... READ MORE

  5. 5. Genomic and transcriptomic sequencing in chronic lymphocytic leukemia

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Diego Cortese; Uppsala universitet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chronic; lymphocytic; leukemia; CLL; genomics; transcriptomics; DNA; RNA; mutations; NGS; whole-exome; sequencing; prognostic; markers; TP53; SF3B1; RPS15; relapse; stereotyped; subsets.;

    Abstract : Identification of recurrent mutations through next-generation sequencing (NGS) has given us a deeper understanding of the molecular mechanisms involved in chronic lymphocytic leukemia (CLL) development and progression and provided novel means for risk assessment in this clinically heterogeneous disease. In paper I, we screened a population-based cohort of CLL patients (n=364) for TP53, NOTCH1, SF3B1, BIRC3 and MYD88 mutations using Sanger sequencing, and confirmed the negative prognostic impact of TP53, SF3B1 or NOTCH1 aberrations, though at lower frequencies compared to previous studies. READ MORE