Search for dissertations about: "leukosialin"

Found 2 swedish dissertations containing the word leukosialin.

  2. 1. Expression and novel function of CD43 in colon cancer cells

    Author : Christian X Andersson; Göteborgs universitet; []
    Keywords : CD43; leukosialin; sialophorin; mucin; nuclear localization; nuclear signaling; Wnt-signaling; beta-catenin; regulated intramembrane cleavage; RIP; proteolytic cleavage;

    Abstract : CD43 is a transmembrane protein containing an extracellular domain that is extensively O-glycosylated, and a relatively large intracellular domain with a conserved sequence between human, rat and mouse. It is frequently expressed in haematopoietic cell lines where it functions as a regulator of cell adhesiveness, a signal transducer and a cytoskeleton-interacting protein. READ MORE

  4. 2. Tumor biological aspects of the mucin-like glycoprotein CD43

    Author : Sirle Laos; Göteborgs universitet; []
    Keywords : CD43; leukosialin; sialophorin; mucin; colon adenoma; proteolytic processing; ; NF-kappaB; p65; chemokine; p53; ARF; Fas; apoptosis; transformation;

    Abstract : Cancer cells overexpress aberrant forms and amounts of mucins, which contribute to tumor development by regulating cell growth, survival, adhesion, invasion and immune responses. CD43, a type I transmembrane protein, is a mucin-like molecule expressed under normal physiological conditions by most hematopoietic cell types. READ MORE