Search for dissertations about: "levodopa"
Showing result 6 - 10 of 30 swedish dissertations containing the word levodopa.
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6. Levodopa- and Neuroleptic-Induced Dyskinesias : Studies on Pharmacological Modification and Processing of Opioid Neuropeptides
Abstract : Dyskinesias or abnormal involuntary movements are a debilitating complication of long-term levodopa treatment of Parkinson’s disease (PD) that is widely experienced and may compromise the efficacy of the drug therapy. Tardive dyskinesia is another important adverse effect seen with antipsychotic drug treatment. READ MORE
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7. Decision Support for Treatment of Patients with Advanced Parkinson’s Disease
Abstract : The overall aim of this thesis was to develop, deploy and evaluate new IT-based methods for supporting treatment and assessment of treatment of advanced Parkinson’s disease. In this condition a number of different motor and non-motor symptoms occur in episodes of varying frequency, duration and severity. READ MORE
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8. The Role of the Cortico-Basal Ganglia-System in Voluntary Movements
Abstract : Bodies with multiple limbs and joints have endless possibilities to move around in their surrounding space. How the nervous system controls this amount of degrees of freedom in motor execution is a question under vigorous debate. READ MORE
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9. Microvascular plasticity and neurovascular coupling in the pharmacotherapy of Parkinson's disease
Abstract : L-DOPA pharmacotherapy in Parkinson’s disease (PD) is associated with adverse effects occurring after a few years of treatment. Among these, dyskinesia (abnormal involuntary movements) is particularly common and potentially disabling. READ MORE
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10. Levodopa pharmacokinetics -from stomach to brain : A study on patients with Parkinson’s disease
Abstract : Parkinson’s disease (PD) is one of the most common neurodegenerative disorders and it is caused by a loss of dopamine (DA) producing neurons in the basal ganglia in the brain. The PD patient suffers from motor symptoms such as tremor, bradykinesia and rigidity and treatment with levodopa (LD), the precursor of DA, has positive effects on these symptoms. READ MORE