Search for dissertations about: "library preparation"

Showing result 16 - 20 of 41 swedish dissertations containing the words library preparation.

  2. 16. Synthesis of Carbohydrate Mimics and Development of a Carbohydrate Epimerisation Method

    Author : Clinton Ramstadius; Ian Cumpstey; Robert Madsen; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Carbohydrate Mimic; Ring-closing Metathesis; Carbohydrate Chemistry; Carbasugar; Aminocarbasugar; Pseudodisaccharide; Glycosidase and Lectin Inhibitors; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

    Abstract : In this thesis the synthesis of several hydrolytically stable carbohydrate mimics with the potential to function as glycosidase or lectin inhibitors are described. This work is presented in Chapters 2-5. READ MORE

  4. 17. Definition of immunoglobulin germline genes by next generation sequencing for studies of antigen-specific B cell responses

    Author : Néstor Vázquez Bernat; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Immunoglobulins play a critical role in the adaptive immune system, existing as cell surface-expressed B cell receptors and secreted antibodies. Circulating antibodies are the main correlate of protective immunity for most vaccines. READ MORE

  5. 18. Synthesis of bioactive natural products and analogues

    Author : Dan Killander; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; SAR; natural product; total synthesis; benzochromene; fluorene; cannabinoid; statin; TRPA1; TSLP; antiprotozoal; nociception; asthma; inflammation;

    Abstract : Natural products have until recently provided the only remedy for treatment of diseases. The development of modern chemistry in the last centuries has opened the door for tapping into the chemical diversity found in nature. Synthetic natural products, together with analogues, are an important piece in the puzzle towards curing many ailments. READ MORE

  6. 19. Structural and Functional Studies of the Density Enhanced Receptor-like Protein Tyrosine Phosphatase DEP-1

    Author : Maria Sörby; Jeroen Hertog; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Onkologi; Oncology; Onkologi; molekylär cellbiologi; Molecular Cellbiology;

    Abstract : Tyrosine phosphorylation is a central mechanism in cellular signalling leading to proliferation, migration or differentiation. Protein tyrosine phosphorylation is regulated by the coordinated actions of protein tyrosine kinases and protein tyrosine phosphatases. READ MORE

  7. 20. Designing Polymers for Biological Interfaces - From Antifouling to Drug Delivery

    Author : Pontus Lundberg; Michael Malkoch; Anders Hult; Scott M. Grayson; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Surface and colloid chemistry; Yt- och kolloidkemi;

    Abstract : Unspecific interactions, at the interface between a synthetic material and an aqueous biological environment, leading to irreversible protein adsorption can cause to undesired consequences. These include fouling of a boat hull or a triggered immune response. READ MORE