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Showing result 1 - 5 of 7 swedish dissertations matching the above criteria.

2. 1. Long QT syndrome in Sweden : founder effects and associated cardiac phenotypes

   Author : Annika Winbo; Annika Rydberg; Eric Schulze-Bahr; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Long QT Syndrome; Jervell and Lange-Nielsen Syndrome; inherited arrhythmia; founder effects; clinical genetics; haplotype analysis; mutation age; founder mutation; clinical phenotype; life-threatening cardiac events; mutation-specific; KCNQ1 gene; modifier genes; sequence variants; risk stratification; risk factor; gender; pediatrik; Pediatrics;

   Abstract : Background: We aimed to increase the knowledge regarding the familial arrhythmogenic disorder Long QT Syndrome (LQTS) and its recessive variant Jervell and Lange-Nielsen Syndrome (JLNS) in Sweden, including prevalences and clinical phenotypes. A specific focus was directed towards two KCNQ1 mutations –p.Y111C and p. READ MORE

4. 2. Applications of Vectorcardiography for Diagnosis and Risk Stratification in Subpopulations at Risk for Life-Threatening Arrhythmias

   Author : Daniel Cortez; Kardiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vectorcardiography; atrial depolarization; ventricular depolarization repolarization;

   Abstract : Introduction: Vectorcardiography, or 3-dimensional electrocardiography is a tool which can be used to identify subtle changes in the electrical forces of the heart, and which can be applied to atrial depolarization, ventricular depolarization and ventricular repolarization for prognostic and diagostic purposes. Methods: Kor’s regression-related and quasi orthogonal methods was used to derive vectorcardiographic parameters from the 12-lead electrocardiogram and applied to a cohort of cryptogenic stroke patients to assess atrial fibrillation, hypertrophic cardiomyopathy patients to assess for ventricular arrhythmias, applied with right-precordial directed quasi orthogonal method to arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVC/D) patients for diagnosis, and applied to ventricular repolarization only to patients with genotype-positive/phenotype-negative Long QT2 syndrome (KNCH2 mutation) to assess for cardiac events. READ MORE

5. 3. Catching broken hearts - Electrocardiography and in-hospital outcome in Takotsubo syndrome versus ST elevation myocardial infarction

   Author : Rickard Zeijlon; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Takotsubo syndrome; ST elevation myocardial infarction; electrocardiography; arrhythmia; mortality; pathophysiology;

   Abstract : BACKGROUND AND AIMS: Takotsubo syndrome (TS) and acute myocardial infarction (AMI) have similar symptoms, non-invasive test results and complications. Whereas AMI is caused by cardiac ischemia, the pathophysiology of TS is incompletely understood. READ MORE

6. 4. Clinical aspects of arterial wall stiffness with a focus on abdominal aortic aneurysm

   Author : Ida Åström Malm; Peter Blomstrand; Rachel De Basso; Niclas Bjarnegård; Per Lindqvist; Jönköping University; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Arterial Stiffness; Pulse Wave Velocity; Abdominal Aortic Aneurysm; Left Ventricle Function; Interleukin 10;

   Abstract : Background: Cardiovascular diseases are the most common type of age-related diseases and can affect health in several ways. As a result of increased life expectancy around the world, the prevalence of cardiovascular diseases is expected to increase. READ MORE

7. 5. Diffuse large B-cell lymphoma : population-based studies of relapse and cardiac complications

   Author : Sara Harrysson; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Diffuse large B-cell lymphoma (DLBCL) is an aggressive life-threatening disease, but it is often possible to cure with immunochemotherapy. Not responding to primary treatment or having a relapse is associated with poor prognosis. However, it has not been well described how large the proportion of patients with relapsed/refractory disease is. READ MORE