Search for dissertations about: "ligand distribution"

Showing result 1 - 5 of 84 swedish dissertations containing the words ligand distribution.

  1. 1. Direct observation of biomolecule adsorption and spatial distribution of functional groups in chromatographic adsorbent particles

    Author : Anders Ljunglöf; Abraham Lenhoff; Uppsala universitet; []
    Keywords : ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; Biotechnology; Confocal microscopy; confocal Raman spectroscopy; protein adsorption; ligand distribution; visualization; imaging; Bioteknik; Bioengineering; Bioteknik; Surface Biotechnology; ytbioteknik;

    Abstract : Confocal microscopy has been used as a tool for studying adsorption of biomolecules to individual chromatographic adsorbent particles. By coupling a fluorescent dye to protein molecules, their penetration into single adsorbent particles could be observed visually at different times during batch uptake. READ MORE

  2. 2. Application of Raman and Fluorescence Spectroscopy to Single Chromatographic Beads

    Author : Mina Larsson; Jan Lindgren; Jean-Claude Lassègues; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; Chemistry; agarose; chelating group; confocal Raman spectroscopy; confocal scanning laser microscopy; gold nanoparticles; ligand distribution; functional group; neodymium; polymer beads; Raman; SERS; surface-enhanced Raman spectroscopy; Kemi; Chemistry; Kemi;

    Abstract : Chromatography is a powerful technique, essential in chemical analyses and preparative separation in industry and research. Many different kinds of chromatographic material are needed, due to the large variety of applications. Detailed methods of characterisation are needed to design new chromatographic materials and understand their properties. READ MORE

  3. 3. Characterization of [18F]flutemetamol binding properties : A β-amyloid PET imaging ligand

    Author : Kerstin Heurling; Mark Lubberink; Jens Sörensen; Julie Price; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Positron emission tomography PET ; molecular imaging; amyloid; tracer validation; Radiology; Radiologi;

    Abstract : The criteria for diagnosing Alzheimer’s disease (AD) have recently been revised to include the use of biomarkers for the in vivo presence of β-amyloid, one of the neuropathological hallmarks of AD. Examples of such biomarkers are positron emission tomography (PET) β-amyloid specific ligands, including [18F]flutemetamol. READ MORE

  4. 4. Galanin : Studies by Modification of the Ligand and the Receptor

    Author : Anders Juréus; Claes-Göran Östeson; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Other chemistry; Övrig kemi; neurokemi och neurotoxikologi; Neurochemistry and Neurotoxicology;

    Abstract : This thesis is devoted to the deeper understanding of the molecular details of the interaction between the neuropeptide galanin and its target protein, the G-protein coupled 7TM galanin receptor. The enzymatic control of galanin degradation and second messenger systems triggered by galanin receptor activation are also studied. READ MORE

  5. 5. On the Character of Active Sites in Copper Exchanged Zeolites during NH3-SCR

    Author : Lin Chen; Chalmers University of Technology; []
    Keywords : NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES; Cu-SSZ-13; SSIE; O2-dissociation; Al-distribution; NH3-SCR; Chabazite; O2-activation;

    Abstract : Nitrogen oxides (NOx) are formed during combustion in diesel engines and one current approach to reduce NOx to N2 is selective catalytic reduction with NH3 as reducing agent (NH3-SCR). To acquire both high activity and selectivity, the active site is often atomically dispersed metal atom, so-called single-site catalysts. READ MORE