Search for dissertations about: "ligands"

Showing result 1 - 5 of 933 swedish dissertations containing the word ligands.

  2. 1. Galanin receptor ligands

    Author : Johan Runesson; Ülo Langel; Lena Mäler; Stockholms universitet; []
    Keywords : Galanin; GALP; GPCR; Agonist; GalR; Chimeric peptide; Inositol phosphate production; Receptor specificity; Neurochemistry and Molecular Neurobiology; neurokemi med molekylär neurobiologi;

    Abstract : In the nervous system galanin primarily displays a modulatory role. The galaninergic system consists of a number of bioactive peptides with a highly plastic expression pattern and three different receptors. The lack of receptor subtype selective ligands and antibodies have severely hampered the charac-terization of this system. READ MORE

  4. 2. Galanin receptor ligands : Design, synthesis, characterization and biological effects

    Author : Kristin Webling; Ülo Langel; Tore Bengtsson; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Abstract : Galanin is a 29/30 amino acid long bioactive peptide discovered over 30 years ago when C-terminally amidated peptides were isolated from porcine intestines. The name galanin originates from a combination of the first and last amino acids - G from glycine and the rest from alanine. READ MORE

  5. 3. Galanin receptor ligands : agonists and the first antagonists

    Author : Tiit Land; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : .... READ MORE

  6. 4. Oxaline-containing ligands : synthesis and applications

    Author : Emmanuel Macedo; KTH; []
    Keywords : ;

    Abstract : .... READ MORE

  7. 5. Asymmetric Hydrogenations : Syntheses of Ligands and Expansion of Substrate Scope

    Author : Pradeep Cheruku; Pher Andesson; Jay Siegel; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Catalysis; Asymmetric; Hydrogenations; Reductions; Olefins; Imines; Enol phosphinates; Transition metal; Complexes; Iridium; Enamines; Ruthenium; Ligands; Trifluoromethyl; Diphenylvinylphosphine oxides; Vinyl phosphonates; Chemistry; Kemi;

    Abstract : Asymmetric hydrogenation has emerged as a versatile methodology to obtain a wide range of chiral precursors. This thesis focused on the synthesis of new chiral ligands and the expansion of the substrate scope of asymmetric hydrogenations. READ MORE