Search for dissertations about: "ligands"

Showing result 41 - 45 of 933 swedish dissertations containing the word ligands.

  2. 41. EGFR- and HER2-Binding Affibody Molecules : Cellular studies of monomeric, dimeric and bispecific ligands

    Author : Lina Ekerljung; Lars Gedda; Johan Lennartsson; Jörgen Carlsson; Birgitta Sundström; Uppsala universitet; []
    Keywords : EGFR; HER2; Affibody molecule; cell signaling; receptor dimerization; Biomedical Radiation Science; Biomedicinsk strålningsvetenskap;

    Abstract : Abnormal expression and signaling of the ErbB receptors is associated with the development and progression of several forms of cancer. In this thesis, new ErbB-targeting affibody molecules are evaluated regarding their cellular effects in vitro. READ MORE

  4. 42. Chiral metallocene ligands for transition metal-catalysed reactions

    Author : Hanna Cotton; Antonio Togni; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Organisk kemi;

    Abstract : .... READ MORE

  5. 43. Construction of binaphthylic ligands via a chiral tether

    Author : Christina Olsson; Stockholms universitet; []
    Keywords : ;

    Abstract : .... READ MORE

  6. 44. The iron centre of ribonucleotide reductase protein R2 of Escherichia coli : effects of protein engineering of the iron ligands

    Author : Bert Ove Persson; Lars-Erik Andréasson; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Molekylärbiologi; Molecular Biology; molekylärbiologi;

    Abstract : .... READ MORE

  7. 45. Evolution of Membrane Bound Proteins and their Ligands : The Melanocortin (MC) Receptor Inverse Agonists AgRP2, ASIP2, Drug/Metabolite Transporters, and SPNS1

    Author : Åke Västermark; Helgi Schiöth; Arne Elofsson; Uppsala universitet; []
    Keywords : ;

    Abstract : Integral membrane proteins play a key role hormonal and neuronal signaling. Transmembrane helix (TM) proteins form about 27% of the human proteome. Furthermore, 44% of the human drug targets are receptors, and 19% of these are seven-transmembrane domain receptors (GPCRs), which constitute 4% of the entire protein-coding genome. READ MORE